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Browsing by Author "Gunasekara, T. D. K. S. C."

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CHARACTERIZATION OF IMMUNOMODULATORY EFFECTS OF SELECTED SRI LANKAN INDIGENOUS HERBAL MEDICINES

Gunasekara, T. D. K. S. C. (University of Ruhuna, 2014-06)

The present study was undertaken to elucidate the immunomodulatory potential of five medicinal plants which are used by traditional and Ayurveda practitioners of Sri Lanka to treat various ailments. Ethanolic extracts ...
Occupational Paraquat and Glyphosate Exposure May Decline Renal Functions among Rural Farming Communities in Sri Lanka

Abdul, K. S. M.; De Silva, P. Mangala C. S.; Ekanayake, E. M. D. V.; Thakshila, W. A. K. G.; Gunarathna, S. D.; Gunasekara, T. D. K. S. C.; Jayasinghe, S. S.; Asanthi, H. B.; Chandana, E. P. S.; Chaminda, G. G. T.; Siribaddana, S. H.; Jayasundara, N. (MDPI, 2021-03-22)

Extensive use of herbicides is common among rural agricultural workers in Sri Lanka. Recent studies have postulated their role in the development of chronic kidney disease of unknown etiology (CKDu). Paraquat and glyphosate ...
Occupational Paraquat exposure among sugarcane and vegetable farmers in Sri Lanka: A case study

Abdul, Mohammed K.S.; Ekanayake, D.V.; Gunasekara, T. D. K. S. C.; Perera, H.A.S.D.; De Siva, B.C.J.; Jayasumana, C.; Chandana, E.P.S.; Jayasinghe, S.S.; De Silva, P.M.C.S. (Institute of Biology, Sri Lanka, 2015-09)

Paraquat (1, 1 – dimethyl -4, 4- bipyridylium dichloride) is a contact herbicide, predominantly used in Sri Lanka. Despite the imposed ban in agriculture sector, Paraquat usage was seen among sugarcane farmers in Pelawatta ...
Urinary biomarkers indicate pediatric renal injury among rural farming communities in Sri Lanka

Gunasekara, T. D. K. S. C.; De Silva, P. M. C. S.; Ekanayake, E. M. D. V.; Thakshila, W. A. K. G.; Pinipa, R. A. I.; Sandamini, P. M. M. A.; Gunarathna, S. D.; Chandana, E. P. S.; Jayasinghe, S. S.; Herath, C.; Siribaddana, S.; Jayasundara, N. (Springer, 2022-05-16)

Pediatric renal injury is an emerging health concern in communities affected by chronic kidney disease of uncertain etiology (CKDu). Early detection of susceptibilities through highly sensitive and specific biomarkers can ...
Urinary Biomarkers of Renal Injury KIM-1 and NGAL: Reference Intervals for Healthy Pediatric Population in Sri Lanka

De Silva, P. Mangala C. S.; Gunasekara, T. D. K. S. C.; Gunarathna, S. D.; Sandamini, P. M. M. A.; Pinipa, R. A. I.; Ekanayake, E. M. D. V.; Thakshila, W. A. K. G.; Jayasinghe, S. S.; Chandana, E. P. S.; Jayasundara, Nishad (Children, 2021-08-09)

Emerging renal biomarkers (e.g., kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL)) are thought to be highly sensitive in diagnosing renal injury. However, global data on reference ...
Urinary cystatin C: pediatric reference intervals and comparative assessment as a biomarker of renal injury among children in the regions with high burden of CKDu in Sri Lanka

Sandamini, P. M. M. A.; De Silva, P. Mangala C. S.; Gunasekara, T. D. K. S. C.; Gunarathna, S. D.; Pinipa, R. A. I.; Herath, C.; Jayasinghe, S. S.; Chandana, E. P. S.; Jayasundara, N. (Springer, 2022-02-02)

Background: Cystatin C (Cys-C) is an emerging biomarker of renal diseases and its clinical use, particularly for screening the communities affected by chronic kidney disease of unknown etiology (CKDu), is hindered due to ...
The Utility of Novel Renal Biomarkers in Assessment of Chronic Kidney Disease of Unknown Etiology (CKDu): A Review

Gunasekara, T. D. K. S. C.; De Silva, P. Mangala C. S.; Herath, C.; Siribaddana, S.; Siribaddana, N.; Jayasumana, C.; Jayasinghe, S. S.; Cardenas-Gonzalez, Maria; Jayasundara, Nishad (MDPI, 2020-12-18)

Chronic Kidney Disease (CKD) is a globally prevalent non-communicable disease with significant mortality and morbidity. It is typically associated with diabetes and hypertension; however, over the last two decades, an ...

Browsing by Author "Gunasekara, T. D. K. S. C."

Browsing by Author "Gunasekara, T. D. K. S. C."

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