Cembrane type diterpenoids from the leaves of Croton oblongifolius Roxb. and their bioactivities

dc.contributor.author	Wijesekera, K.
dc.date.accessioned	2023-03-20T09:26:30Z
dc.date.available	2023-03-20T09:26:30Z
dc.date.issued	2017-12-07
dc.identifier.citation	Wijesekera, K. (2017). Cembrane type diterpenoids from the leaves of Croton oblongifolius Roxb. and their bioactivities. Ruhuna Journal of Medicine, 5(1), 7-11.	en_US
dc.identifier.uri	http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/11999
dc.description.abstract	Current study focused on the isolation, characterization and evaluation of biological activities of secondary metabolites from C. oblongifolius. Two cembrane type ditepenes; crotocembranal and crotocembraneic acid were isolated. Structures of the compounds were elucidated by analysing spectroscopic data. Cytotoxicity, cancer chemopreventive properties antibacterial activities were tested. Both compounds showed mild cytotoxicity towards the cancer cell line tested. Crotocembraneic acid exhibited minimum inhibitory concentration of (MIC) of 25 ug/ml for Mycobacterium tuberculosis H37Ra and 100 ug/ml for Staphylococcus epidermidis. Crotocembranal was inactive as an anti-infective agent.	en_US
dc.language.iso	en	en_US
dc.publisher	Ruhuna Journal of Medicine	en_US
dc.subject	Croton oblongifolius	en_US
dc.subject	Diterpenoids	en_US
dc.title	Cembrane type diterpenoids from the leaves of Croton oblongifolius Roxb. and their bioactivities	en_US
dc.type	Article	en_US