dc.contributor.author |
Kalansuriya, P. |
|
dc.contributor.author |
Quezada, Michelle |
|
dc.contributor.author |
Espó sito, Breno P. |
|
dc.contributor.author |
Capon, Robert J. |
|
dc.date.accessioned |
2023-09-11T05:37:59Z |
|
dc.date.available |
2023-09-11T05:37:59Z |
|
dc.date.issued |
2017-03-24 |
|
dc.identifier.citation |
Kalansuriya, P., Quezada, M., Esposito, B. P., & Capon, R. J. (2017). Talarazines A–E: Noncytotoxic iron (III) chelators from an Australian mud dauber wasp-associated fungus, Talaromyces sp.(CMB-W045). Journal of Natural Products, 80(3), 609-615. |
en_US |
dc.identifier.uri |
http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/14551 |
|
dc.description.abstract |
ABSTRACT: Chemical analysis of an Australian mud dauber wasp-associated fungus, Talaromyces sp. (CMB-W045), yielded five new coprogen siderophores, talarazines A−E( 1−5), together with dimerumic acid (6), desferricoprogen (7), and elutherazine B (8). Structures inclusive of absolute configuration were assigned on the basis of detailed spectroscopic analysis and application of the C3 Marfey’s method. We report on the noncytotoxic Fe(III) chelation properties of 1−8 and demonstrate that biosynthesis is regulated by available Fe(III) in culture media. We demonstrate a magnetic nanoparticule approach to extracting high-affinity Fe(III) binding metabolites (i.e., 8) from complex extracts. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
American Chemical Society and American Society of Pharmacognosy |
en_US |
dc.title |
Talarazines A−E: Noncytotoxic Iron(III) Chelators from an Australian Mud Dauber Wasp-Associated Fungus, Talaromyces sp. (CMB-W045) |
en_US |
dc.type |
Article |
en_US |