Evaluation of the Efficacy of Melothria Maderaspatana in the Alleviation of Carbon Tetrachloride-induced Liver Dysfunction

dc.contributor.author	Thabrew, M.I.
dc.contributor.author	Jayatilaka, K.A.P.W.
dc.contributor.author	Perera, D.J.
dc.date.accessioned	2023-10-05T07:48:59Z
dc.date.available	2023-10-05T07:48:59Z
dc.date.issued	1988-07-01
dc.identifier.citation	Thabrew MI, Jayatilaka KA, Perera DJ. Evaluation of the efficacy of Melothria maderaspatana in the alleviation of carbon tetrachloride-induced liver dysfunction. J Ethnopharmacol. 1988 Jul-Aug;23(2-3):305-12. doi: 10.1016/0378-8741(88)90010-4. PMID: 3193793.	en_US
dc.identifier.uri	http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/14978
dc.description.abstract	An investigation was carried out to evaluate the ability of Melothria maderaspatana to protect the livers of albino rats from carbon tetrachloride-mediated alterations in liver histopathology and serum levels of alanine aminotransferase, aspartate aminotransferase and alkaline phosphatase. Treatment with an aqueous extract of Melothria aerial parts (either before or after CCl4 administration) markedly decreased CCl4-mediated alterations in liver histopathology as well as serum enzyme levels. Results provide supportive evidence for the folklore view that this plant is a good hepatotonic	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier	en_US
dc.subject	Carbon Tetrachloride Poisoning	en_US
dc.subject	drug-Induced Liver Injury	en_US
dc.subject	plant Extracts	en_US
dc.title	Evaluation of the Efficacy of Melothria Maderaspatana in the Alleviation of Carbon Tetrachloride-induced Liver Dysfunction	en_US
dc.type	Article	en_US