Prevalence of Insulin Resistance Syndrome (IRS) among young patients with newly diagnosed type 2 diabetes

Abstract

Incidence o f type 2 diabetes is reaching epidemic proportions in the South Asian region1. A notable feature among subjects affected with type 2 diabetes is the presence o f features o f insulin resistance. Insulin resistance can be assessed in several ways. The gold standard is the euglycaemic clamp method which is cumbersome2. Several other simple measurements o f insulin resistance have been recognized. These include fasting insulin / glucose ratio, the presence o f more than three biochemical abnormalities including high blood pressure, elevated serum levels o f triglycerides and subnormal levels o f HDL cholesterol. We estimated the prevalence o f clinical and biochemical markers o f IRS among a cohort o f newly diagnosed type 2 diabetic subjects under the age o f 45 years.