Determining the toxicity of papaya (Carica papaya) leaf  extract on zebrafish (Danio rerio) embryos

dc.contributor.author	Prameesha, H.A.
dc.contributor.author	Guruge, W.A.H.P.
dc.contributor.author	De Silva, D.P.N.
dc.date.accessioned	2022-03-15T04:23:36Z
dc.date.available	2022-03-15T04:23:36Z
dc.date.issued	2022-01-19
dc.identifier.issn	1391-8796
dc.identifier.uri	http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/5548
dc.description.abstract	Herbal drugs becoming popular in medicine as well as in other fields including aquaculture. Papaya (Carica papaya) has proven antibacterial, anti-inflammatory and anti-tumor properties. However, the toxicity of papaya leaf extract needs to be tested to determine the teratogenic effects. Zebrafish (Danio rerio) embryo toxicity testing is one of the standard methods used in toxicological assays. Hence, present study investigated the acute toxicity effect of wild type papaya leaf extract on Zebrafish embryos. Zebrafish embryos (16 cell stage) were exposed to four different concentrations of aqueous papaya leaf extracts as 200, 150, 100 and 50 mg/ml (36 embryos per treatment). Distilled water was used as negative control while tetracycline (2 mg/ml) suspension was used as positive control.	en_US
dc.language.iso	en	en_US
dc.publisher	Faculty of Science, University of Ruhuna, Matara, Sri Lanka	en_US
dc.subject	Herbal antibiotics	en_US
dc.subject	Papaya leaf extract	en_US
dc.subject	Toxicity	en_US
dc.subject	Zebrafish embryo	en_US
dc.title	Determining the toxicity of papaya (Carica papaya) leaf extract on zebrafish (Danio rerio) embryos	en_US
dc.type	Article	en_US