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Browsing Department of Medical Laboratory Science by Subject "Breast cancer"

Now showing items 1-7 of 7

Awareness of female malignancies among women and their partners in Southern Sri Lanka and implications for screening: a cross sectional study

Witharana, Chamindri; Wijesiriwardhana, Prabhavi; Jayasekara, Kalani; Kumari, Priyanka; Rodrigo, Chaturaka (BMC, 2015-11-25)

Background: The incidences of breast, cervical and uterine malignancies continue to increase in Sri Lanka. It is important to explore the awareness of both women and their male partners regarding these malignancies ...
Elevated pre-surgical CA15-3: does it predict the short-term disease-free survival of breast cancer patients without distant metastasis?

Mudduwa, L.K.B.; Wijayaratne, G.B.; Peiris, H.H.; Gunasekera, S.N.; Abeysiriwardhana, D.; Liyanage, N. (International Journal of Women's Health, 2018)

Background: CA15-3 is the most commonly used tumor marker in breast cancer. Its prognostic role has been described in the metastatic setting, but the role of pre-surgical CA15-3 in the assessment of patients with breast ...
KIBRA; a novel biomarker predicting recurrence free survival of breast cancer patients receiving adjuvant therapy

Mudduwa, L.; Peiris, H.; Gunasekara, S.; Abeysiriwardhana, D.; Liyanage, N.; Rayala, S.K.; Liyanage, T. (BMC Cancer, 2018-05-24)

Background: This study was carried out to evaluate the prognostic value of KIBRA in breast cancer. Methods: This retrospective study included breast cancer patients who sought the services of the immunohistochemistry laboratory ...
Molecular classification of breast cancers using immunohistochemical surrogates; the Sri Lankan experience

Mudduwa, L.; Peiris, H.; Liyanage, L.; Abeysiriwardhana, D. (Journal of Diagnostic Pathology, 2019-06-30)

Background: Breast cancer diagnosis has evolved over the past decades. Today, it is vital to classify breast cancers according to genetic expression. Immunohistochemical surrogates have been identified as a cost-effective ...
Outcome based validation of Nottingham Prognostic Index in a Sri Lankan setting

Peiris, H.H.; Mudduwa, L.K.B.; Thalagala, N.I.; Jayatilaka, K.A.P.W.; Ekanayaka, U.; Horadugoda, J. (University of Ruhuna, Matara, Sri Lanka, 2016-03-19)

Nottingham prognostic index (NPI) is widely used to stratify breast cancer (BC) patients into prognostic groups; good (I=≤3.4), moderate (II=3.4-5.4) and poor (III=>5.4). Although it has been in use for many years it has ...
Validity of St Gallen risk categories in prognostication of breast cancer patients in Southern Sri Lanka

Peiris, H.; Mudduwa, L.; Thalagala, N.; Jayatilake, K. (BMC Women's Health, 2018-01-31)

Background: Although, there are many developments in the field of management, breast cancer is still the commonest cause of cancer related deaths in women in Sri Lanka. This emphasizes the need for validation of treatment ...
The value of Nottingham grade in breast cancer re-visited in the Sri Lankan setting

Peiris, H.; Mudduwa, L.; Thalagala, N.; Jayatialake, K. (Malays J Pathol, 2017-08)

Objective: We aimed to assess the impact of Nottingham grade (NG) on breast cancer specific survival (BCSS) and recurrence free survival (RFS) of operable breast cancer (BC) patients presenting at different TNM stages ...

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