Scholarly Publications: Recent submissions

Now showing items 441-460 of 8531

Visual Detection of Filaria-specific IgG4 in Urine using Red-colored High Density Latex Beads

Fumiaki Nagaoka; Makoto Itoh, Mohammad S Samad; Hidekazu Takagi; Weerasooriya, M.V.; Yahathugoda, T.C.; Moazzem Hossain; Kazuhiko Moji; Eisaku Kimura; Samad, Mohammad S. (Elsevier, 2012-09-06)

The use of urine for the immunodiagnosis of lymphatic filariasis has a definite advantage: the sample collection is not invasive and thus well accepted by people. Urine-based ELISA to detect filaria-specific IgG4 has been ...
Effects of 5 Rounds of Mass Drug Administration with Diethylcarbamazine and Albendazole on Filaria-specific IgG4 Titers in Urine: 6-year Follow-up Study in Sri Lanka

Makoto Itoh; Weerasooriya, M.V.; Yahathugoda, T.C.; Hidekazu Takagi; Samarawickrema, Wilfred A.; Fumiaki Nagaoka; Eisaku Kimura (Elsevier, 2011-06-24)

ELISA for filaria-specific IgG4 in urine (urine ELISA) was applied to children in 7 schools in Sri Lanka, before and after 5 rounds of annual mass drug administration (MDA). The pre-treatment IgG4 prevalence in 2002 was ...
Development of loop-mediated Isothermal Amplification Method for Detecting Wuchereria Bancrofti DNA in Human Blood and Vector Mosquitoes

Hidekazu Takagi; Makoto Itoh; Shinji Kasai; Yahathugoda, T.C.; Weerasooriya, M.V.; Eisaku Kimura (Elsevier, 2011-09-10)

We have developed loop-mediated isothermal amplification (LAMP) method to detect Wuchereria bancrofti DNA. The sensitivity and specificity of LAMP method were equivalent to those of PCR method which detects SspI repeat ...
Expanded New Born Screening (eNBS) Panel for Sri Lanka: stakeholder Opinion

Arachchige, C.P.I.K.; Liyanage, D.; Egodage, U.K.; Dasanayake, D.L.W.; Gunarathna, D.A.; Amarasena, S.; Hettiarachchi, M. (BMJ Publishing Group Ltd, 2023-06-19)

Objectives Newborn screening helps to identify inherited disorders at their asymptomatic stage and intervene before babies go into the symptomatic phase. A number of Inherited Metabolic Disorders (IMDs) are being screened ...
Expression of Antiradical Power of Pigmented and Non-pigmented Rice (Oryza sativa L.) Varieties in Relation to their Colour Strengths Before and After Polishing

Harsha Kumara, K.H.C.; Hafeel, R.F.; Bulugahapitiya, V.P.; Bentota, A.P.; De Zoysa, G.E.D.; Herath, H.M.S. (International Symposium on Agriculture and Environment 2020University of Ruhuna, Sri Lanka, 2020-02)

Natural antioxidants have potential to counterbalance the effect of anti-oxidative stress and the deleterious effect on human health caused due to the synthetic antioxidants. Rice is one of the rich sources for antioxidants. ...
A Comparative Investigation on Agronomic Traits of Popularly Grown Improved and Traditional Varieties of Rice.

Hafeel, R.F.; Bulugahapitiya, V.P.; Bentota, A.P.; De Zoysa, G.E.D. (Annual sessions of Sri Lanka Association for the Advancement of Science (SLAAS)., 2018)

Rice is the staple food of Sri Lankans and it is available mainly in different categories such as improved and traditional varieties. Presently, most cultivation (99%) are improved rice varieties,while about 1% of ...
10 Quality and Safety of Herbal Medicinal Products

Napagoda, M.; Wijesundara, D.S.A.; Jayasinghe, L. (De Gruyter, 2022)

The World Health Organization defines herbal medicines as plant-derived materials orpreparations intended for human therapeutic use or for other health benefits in hu-mans [1, 2]. Nevertheless, most of the traditional ...
Effect of Alendronate and Vitamin D 3 Treatment on Bone Turnover Markers in Postmenopausal Women with High Fracture Risk: a Double-blind, Randomized Controlled Trial.

Rathnayake, H.; Lekamwasam, S.; Wickramatilake, C.M.; Lenora, J. (80th Annual Academic Sessions of the GMA-(oral), 2021-12)

Background: Bone turnover markers (BTMs) are increased after menopause in women. BTMs are expected to decrease significantly after receiving anti-resorptive treatment in osteoporosis and they can be used to monitor the ...
Association of Bone Turnover Markers with Trabecular Bone Score and Bone Mineral Density among Pre- and Postmenopausal Women: a Study from Sri Lanka

Rathnayake, H.; Lekamwasam, S.; Wickramatilake, C.M.; Lenora, J. (Osteoartheritis and Musculoskeletal Diseases (WCO IOF-ESCEO) (Virtual)-poster, 2021-12)

Objective: Data on the association between bone turnover markers (BTMs) and BMD/trabecular bone score (TBS) are not available for Sri Lankans. This study evaluated the association of serum BTMs with BMD and TBS among pre- ...
Antimicrobial Activity of Leaf Extracts of Litsea iteodaphne (“Kalu Nika”) Against Clinical Isolates of Methicillin Resistant Staphylococcus Aureus

Janesha, U.G.S.; Hasanga, M.R.P.; Hewawasam, R.P.; Wijayaratne, W.M.D.G.B. (2020-11-13)

The use of higher plants to treat infectious diseases is an age-old practice in a large part of the world population, where there is reliance on traditional medicine for a variety of diseases [1]. Interest in plants with ...
In vitro Evaluation of the Antimicrobial Activity of Leaf Extracts of Litsea iteodaphne Against a Selected Group of Bacteria Including Methicillin-Resistant Staphylococcus aureus

Janesha, U.G.S.; Rathnayake, H.; Hewawasam, R.P.; Wijayaratne, W.M.D.G.B. (Wolters Kluwer-Medknow, 2020-05-29)

Background: The quest for scientific endorsement of new drugs from plants continues due to the rising antibiotic resistance against pathogenic bacteria. Litsea iteodaphne is used in Sri Lanka in the treatment of infectious ...
Screeningof the Antibacterial Activities of the Crude Extracts of the Lichen, Parmotrema tinctorum Against Gram Positive and Negative Pathogenic Bacteria

Shiromi, P.S.A.I.; Hasanga, M.R.P.; Hewawasam, R.P.; Wijayaratne, W.M.D.G.B.; Jayalal, R.G.U. (Sabaragamuwa University of Sri Lanka, 2019-11-14)

Among the global health problems in the 21st century, antibiotic resistance is considered as an exigent challenge emerged mainly due to the indiscriminate use of antibiotics during various infectious diseases. Therefore, ...
GSTM2 C Terminus Reduces Calcium Release Through RyR2 in Spontaneously Contracting and Field Stimulated Ventricular Cardiomyocytes

Hewawasam, R.P.; Casarotto, Marco G.; Board, Philip G.; Dulhunty, Angela F. (Elsevier, 2011-02-01)

The ryanodine receptor (RyR) is an ion channel that releases Ca2+ from the sarcoplasmic reticulum and is essential for excitation-contraction coupling and contraction in striated muscle. Previously we reported that the ...
Regulation of the Cardiac Muscle Ryanodine Receptor by Glutathione Transferases

Dulhunty, Angela F.; Hewawasam, R.P.; Dan Liu; Casarotto, Marco G.; Board, Philip G. (Taylor & Francis, 2011-05-01)

Glutathione transferases (GSTs) are generally recognized for their role in phase II detoxification reactions. However, it is becoming increasingly apparent that members of the GST family also have a diverse range of other ...
Screening for Obstructive Sleep Apnoea in Overweight and Obese Children in Southern Sri Lanka

De Silva, M.H.A.D.; Hewawasam, R.P.; Chamika, R.M.A. (Galle Medical Association, 2022-09-27)

Introduction: One of the main risk factors of obstructive sleep apnoea (OSA) is childhood obesity which account for about 60% incidence in obese children. Although polysomnography is the gold standard, it is costly and ...
Aqueous bark Extract of Nauclea Orientalis (Bak mee) Attenuates Doxorubicin Induced Inflammation and Apoptosis in Wistar rats

Sandamali, J.A.N.; Hewawasam, R.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (Faculty of Allied Health Sciences University of Sri Jayewardenepura, 2021)
Electrocardiographic and Biochemical Analysis of Anthracycline Induced Cardiotoxicity in Breast Cancer Patients from Southern Sri Lanka

Sandamali, J.A.N.; Hewawasam, R.P.; Fernando, M.A.C. Sri Sampath; Jayatilaka, K.A.P.W. (BioMed Central, 2023-03-04)

Background: The clinical application of anthracycline chemotherapy is hindered due to the cumulative dose-dependent cardiotoxicity followed by the oxidative stress initiated during the mechanism of action of anthracyclines. ...
The Accuracy of Fatty Liver Index for the Screening of Overweight and Obese Children for Non-alcoholic Fatty Liver Disease in Resource Limited Settings

De Silva, M.H.A.D.; Hewawasam, R.P.; Kulatunge, C.R.; Anjali Chamika, R.M. (BioMed Central, 2022-08-30)

Background: Non-alcoholic fatty liver disease (NAFLD) has become the most common liver disease among children with a higher prevalence among obese. Fatty liver index (FLI), an algorithm derived to screen NAFLD using the ...
Cord Leptin, C-Peptide and Insulin Levels in Large for Gestational Age Newborns in Sri Lanka

De Silva, M.H.A.D.; Hewawasam, R.P.; Gayani Iresha, M.A. (Hindawi, 2019-12-16)

Background: Large for gestational age (LGA) infants are more prone to be obese and are at a higher risk of metabolic complications later in life. It is established that Asians have lower skeletal muscle mass and excess ...
Antiurolithiatic Potential of Three Sri Lankan Medicinal Plants by the Inhibition of Nucleation, Growth, and Aggregation of Calcium Oxalate Crystals In Vitro

Hewagama, S.P.; Hewawasam, R.P. (Hindawi, 2022-12-04)

Background: Deposition and formation of stones in any part of the urinary system is called urolithiasis. CaOx is the predominant component of most stones, and the formation of these stones is a multistep process that ...

Now showing items 441-460 of 8531

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