dc.contributor.author |
Kariyawasam, A. G. T. A. |
|
dc.contributor.author |
Fernando, C. L. |
|
dc.contributor.author |
De Silva, P. U. T. |
|
dc.contributor.author |
Sanjeewa, A. D. S. S. |
|
dc.contributor.author |
Wijewickrama, D. N. |
|
dc.contributor.author |
Herath, H. M. M. |
|
dc.contributor.author |
Weerarathna, T. P. |
|
dc.date.accessioned |
2023-07-26T06:00:59Z |
|
dc.date.available |
2023-07-26T06:00:59Z |
|
dc.date.issued |
2020-01-31 |
|
dc.identifier.citation |
Kariyawasam AGTA, Fonseka CL, De Silva PUT, Sanjeewa ADSS, Wijewickrama DN, Herath HMM, Weerarathna TP. Frequently Relapsing Anterior Nodular Scleritis as the Initial Presentation of a Lethal Systemic Infection: Disseminated Tuberculosis with HIV Coinfection. Case Rep Infect Dis. 2020 Jan 31;2020:9020864. doi: 10.1155/2020/9020864. PMID: 32082660; PMCID: PMC7013353. |
en_US |
dc.identifier.uri |
http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/13840 |
|
dc.description.abstract |
Background.Scleritisisapainfulinflammatoryoculardiseaseoftenassociatedwithanunderlyingsystemicillnessmostlyhaving an autoimmune aetiology.Tuberculosis usuallypresentsas pulmonaryinfection, andthe ocularpresentationis consideredtobe rare.Casepresentation.Wepresentamalewhodevelopedprolongedpyrexiafollowingsystemicsteroidswhilebeinginvestigated forafrequentlyrelapsinganteriorscleritis.Biopsyofsclerademonstratedacid-fastbacilli,andhistologyofscleraandlymphnode showedgranulomatousinflammationwithcaseation.ContrastCTdemonstratedmediastinalandviscerallymphadenopathywith pulmonarychangessuggestingdisseminatedtuberculosis.Later,WesternblotconfirmedcoinfectionwithHIVwithaCD4count of71cells/mm3.Hewastreatedwithantituberculousmedications,andthenHAARTwasinitiatedwithintwomonths.Heshowed good response and showed a partial resolution of scleritis at the end of two months. Conclusion. Tuberculosis tends to occur in unusualsiteswhencoinfectedwithHIV.Scleritisisarareextrapulmonarymanifestationoftuberculosis.Highdegreeofsuspicion is critical in making diagnosis and commencing early treatment. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Hindawi |
en_US |
dc.title |
Frequently Relapsing Anterior Nodular Scleritis as the Initial Presentation of a Lethal Systemic Infection: Disseminated Tuberculosis with HIV Coinfection |
en_US |
dc.type |
Article |
en_US |