Antimicrobial Activity and Oral Acute Toxicity Effect of Cardiospermum  halicacabum Trim Extracts

dc.contributor.author	Dissanayake, D.R.S.G.
dc.contributor.author	Peiris, H.H.
dc.contributor.author	Attanayake, A.P.
dc.date.accessioned	2021-07-30T06:06:38Z
dc.date.available	2021-07-30T06:06:38Z
dc.date.issued	2021-03-03
dc.identifier.issn	2362-0412
dc.identifier.uri	http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/3380
dc.description.abstract	The acute respiratory tract infections are the most common illness in humans, with a high global burden. The present study was to determine the antimicrobial activity of aqueous, ethyl acetate and hexane extracts of Cardiospermum halicacabum Trim (Family: Sapindaceae, Common name: Wel penela) against respiratory tract pathogens and to assess acute oral toxic effects of the above extracts in healthy Wistar rats. The antimicrobial activity was evaluated against a Gram-positive organism; Staphylococcus aureus ATCC 25923 and Gram-negative organisms; Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853. The agar disc diffusion method was performed to estimate the antimicrobial activity according to the Clinical and Laboratory Standards Institute (CLSI) protocols and the diameter of inhibition zones were measured.	en_US
dc.language.iso	en	en_US
dc.publisher	University of Ruhuna	en_US
dc.subject	Acute toxicity	en_US
dc.subject	Antimicrobial activity	en_US
dc.subject	Cardiospermum Halicacabum	en_US
dc.title	Antimicrobial Activity and Oral Acute Toxicity Effect of Cardiospermum halicacabum Trim Extracts	en_US
dc.type	Article	en_US