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Scholarly Publications of Academic Members: Recent submissions

  • Arsenic and Human Health Effects: a Review 
    Chandana, E.P.S.; Jayasumana, C.; De Silva, P.M.C.S.; Abdul, K.S.M.; (Elsevier, 2015-11-01)
    Arsenic (As) is ubiquitous in nature and humans being exposed to arsenic via atmospheric air, ground water and food sources are certain. Major sources of arsenic contamination could be either through geological or via ...
  • Lipid Abnormalities in type 2 Diabetes Mellitus Patients in Sri Lanka 
    Hettihewa, L.M.; Gunasekera, S.W.; Jayasinghe, S.S.; Palangasinghe, S.; Weerarathna, T.P.; Kotapola, I. (Galle Medical Association, 2009-09-25)
    Background & Objective: Previous studies suggest that the prevalence of dyslipidaemia in type 2 diabetes is high with respect to the general population. But data related to the prevalence of dyslipidaemia in ...
  • Genetic Association Between Insulin Resistance And Total Cholesterol In Type 2 Diabetes Mellitus - A Preliminary Observation 
    Hettihewa, L.M.; Jayasinghe, S.S.; Weerarathna, T.P.; Gunasekara, S.W.; Palangasinghe, S.; Kotapola, I. (OJHAS, 2005-05-10)
    We investigated the degree of genetic association between insulin resistance (IR) with type 2 diabetes mellitus (DM) and abnormalities in lipid metabolism in 42 patients. IR was assessed by fasting insulin test ...
  • Correlation Between Changes of Blood Pressure with Insulin Resistance in type 2 Diabetes Mellitus with 4 weeks of Pioglitazone Therapy 
    Hettihewa, L.M.; Jayasinghe, S.S.; Imendra, K.G.; Weerarathna, T.P. (Springer, 2008-01)
    Objective: To examine effects of pioglitazone (PIO) on systolic, diastolic, pulse and mean blood pressures (SBP, DBP, PP and MP, respectively) in type 2 diabetes mellitus (T2DM). Materials and methods: One hundred and ...
  • Correlation Between BMI and Insulin Resistance in type 2 Diabetes Mellitus Patients on Pioglitazone Treatment 
    Hettihewa, L.M.; Dharmasira, L.P.; Ariyaratne, C.D.; Jayasinghe, S.S.; Weerarathna, T.P.; Kotapola, I.G. (Galle Medical Association, 2009-09-25)
    doi: 10.4038/gmj.v12i1.1080 Galle Medical Journal Vol.12(1) 2007 18-24
  • Simple and Sensitive Liquid Chromatography–tandem mass Spectrometry Methods for Quantification of Paraquat in Plasma and Urine: application to experimental and clinical toxicological studies 
    Wunnapuk, Klintean; Medley, Gregory A.; Liu, Xin; Grice, Jeffrey E.; Jayasinghe, S.S.; Gawarammana, I.; Buckley, Nicholas A.; Roberts, Michael S. (Elsevier, 2011-10-15)
    Simple, sensitive and specific liquid chromatography–tandem mass spectrometry (LC–MS/MS) methods have been developed and validated for quantification of paraquat (PQ) in plasma and urine. Plasma and urine sample preparation ...
  • Saline Toxicity and Antioxidant Response in Oryza sativa: An Updated Review 
    Mosur, Mahmuda Binte; Datta, Juel; Rohman, Motiar; Hasanuzzaman, Mirza; Hossain, Akbar; Islam, Mohammad Sohidul; Bukhari, Maham Asif; Jabeen, Tasmiya; Mubeen, Muhammad; Nasim, Wajid; Rehman, Abdul; Ratnasekera, Disna; Llanes, Analía; Athar, Habib-ur-Rehman; Iqbal, Muhammad Aamir; Ahmed, Sharif; Gill, Rafaqat Ali; Ue, Akihiro; Liyun, Liu; Skalicky, Milan; Brestic, Marian; Erman, Murat; Kaya, Yüksel; Sabagh, Ayman El (Springer, 2022)
    Abiotic stresses such as drought, waterlogging, extreme temperatures, salinity, and mineral toxicity negatively impact the growth and development, yield, and seed quality of crop plants. Presently, abiotic stresses are ...
  • Insights into Potential Roles of Plants as Natural Radioprotectants and Amelioration of Radiations Induced Harmful Impacts on Human Health 
    Naz, MIsbah; Shah, Tariq; Battaglia, Martin; Islam, Mohammad Sohidul; Hossain, Akbar; Iqbal, Muhammad Aamir; Ihsan, Muhammad Zahid; Arif, Md Tahjib-Ul; Dubey, Anamika; Raj, Aman; Kumar, Ashwani; Hakeem, Khalid Rehman; Ratnasekera, Disna; Irfan, Muhammad; Pakyürek, Mine; Kumari, Arpna; Javed, Talha; Shabbir, Rubab; Arslan, Hüseyin; Arslan, Doğan; Özyazici, Gülen; Sabagh, Ayman El (Springer, 2022)
    Radiations have a significant impact on many physiological, biochemical and molecular processes in plants, animals, and humans. Several studies have revealed the beneficial and adverse effects of radiation on human health. ...
  • Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka 
    De Silva, P.M.C.S.; Abdul, K.S.M.; Ekanayake, E.M.D.V.; Jayasumana, C.; Jayasinghe, S.S.; Asanthi, H.B.; Perera, H.S.D.; Chaminda, G.G.T.; Chandana, E.P.S.; Siribaddana, S.H. (PLOS, 2019-09-19)
    Chronic Kidney Disease of uncertain etiology (CKDu) is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that ...
  • Advances in Input Management for Food and Environmental Security 
    Sabagh, Ayman El; Islam, Mohammad Sohidul; Hossain, Akbar; Iqbal, Muhammad Aamir; Rahman, Muhammad Habib Ur; Mansour, Fatma; Wasaya, Allah; Ahmed, Sharif; Singhal, Rajesh Kumar; Kumari, Arpna; Kassahun, Mengesha; Danish, Subhan; Hossain, Mohammad Anwar; Raza, Mohamad Ali; Ratnasekera, Disna; Arif, Muhammad; Fahad, Shah ; Laing, A.M.; Skalicky, Milan; Brestic, Marian (Springer, 2022)
    Achieving food security while protecting the environment in the context of future global climate changes is a great challenge to the sustainability of modern agricultural systems. Food production is likely to maintain ...
  • Administration of Paracetamol to Children; do Parents Adhere to Recommendations? 
    Wanni Arachchi, T.I.; Gamage, M.W.K.; Jayasinghe, S.S. (Galle Medical Association, 2018-12-31)
    Introduction: Fever is a common health problem in childhood. Parents often administer paracetamol to children without consulting a doctor since it is a widely available over the counter drug. The aim of this study was to ...
  • The Utility of Novel Renal Biomarkers in Assessment of Chronic Kidney Disease of Unknown Etiology (CKDu): A Review 
    Gunasekara, T.D.K.S.C.; De Silva, P. Mangala C.S.; Herath, C.; Siribaddana, S.; Siribaddana, N.; Jayasumana, C.; Jayasinghe, S.S.; Cardenas-Gonzalez, Maria; Jayasundara, N. (MDPI, 2020-12-18)
    Chronic Kidney Disease (CKD) is a globally prevalent non-communicable disease with significant mortality and morbidity. It is typically associated with diabetes and hypertension; however, over the last two decades, an ...
  • Occupational Paraquat and Glyphosate Exposure May Decline Renal Functions among Rural Farming Communities in Sri Lanka 
    Abdul, K.S.M.; De Silva, P.M.C.S.; Ekanayake, E.M.D.V.; Thakshila, W.A.K.G.; Gunarathna, S.D.; Gunasekara, T.D.K.S.C.; Jayasinghe, S.S.; Asanthi, H.B.; Chandana, E.P.S.; Chaminda, G.G.T.; Siribaddana, S.H.; Jayasundara, N. (MDPI, 2021-03-22)
    Extensive use of herbicides is common among rural agricultural workers in Sri Lanka. Recent studies have postulated their role in the development of chronic kidney disease of unknown etiology (CKDu). Paraquat and glyphosate ...
  • Prevalence of CKD of Unknown Etiology and its Potential Risk Factors in a Rural Population in Sri Lanka 
    Wijewickrama, E.S.; Gayani, T.W.A.; Ekanayake, E.M.D.V.; Gunasekara, T.D.K.S.; Chandana, E.P.S.; Jayasinghe, S.S.; Ruwanpathirana, T.; Jayasinghe, S.; De Silva, M.C.S. (Elsevier, 2022-08-03)
    Chronic kidney disease of unknown etiology (CKDu) is an emerging form of CKD that predominantly affects working-age adults belonging to agricultural communities living in discrete geographic areas. Disease hotspots have ...
  • Urinary Biomarkers of Renal Injury KIM-1 and NGAL: Reference Intervals for Healthy Pediatric Population in Sri Lanka 
    De Silva, P. Mangala C.S.; Gunasekara, T.D.K.S.C.; Gunarathna, S.D.; Sandamini, P.M.M.A.; Pinipa, R.A.I.; Ekanayake, E.M.D.V.; Thakshila, W.A.K.G.; Jayasinghe, S.S.; Chandana, E.P.S.; Jayasundara, N. (Children, 2021-08-09)
    Emerging renal biomarkers (e.g., kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL)) are thought to be highly sensitive in diagnosing renal injury. However, global data on reference ...
  • Urinary biomarkers indicate pediatric renal injury among rural farming communities in Sri Lanka 
    Gunasekara, T.D.K.S.C.; De Silva, P.M.C.S.; Ekanayake, E.M.D.V.; Thakshila, W.A.K.G.; Pinipa, R.A.I.; Sandamini, P.M.M.A.; Gunarathna, S.D.; Chandana, E.P.S.; Jayasinghe, S.S.; Herath, C.; Siribaddana, S.; Jayasundara, N. (Springer, 2022-05-16)
    Pediatric renal injury is an emerging health concern in communities affected by chronic kidney disease of uncertain etiology (CKDu). Early detection of susceptibilities through highly sensitive and specific biomarkers can ...
  • Autonomic Function following Acute Organophosphorus Poisoning: A Cohort Study 
    Jayasinghe, S.S.; Pathirana, K.D. (Plos One, 2012-05-24)
    Autonomic dysfunction after chronic low level exposure to organophosphorus (OP) pesticides has been consistently reported in the literature, but not following a single acute overdose. In order to study autonomic function ...
  • Prospective Role of Plant Growth Regulators for Tolerance to Abiotic Stresses 
    Sabagh, Ayman El; Hossain, A.; Islam, M.S.; Iqbal, M.A.; Mubeen, M.; Nasim, W.; Wasaya, A.; Llanes, A.; Ratnasekera, D.; Singhal, R.K.; Kumari, A.; Meena, R.S.; Abdelhamid, M.; Hasanuzzaman, M.; Raza, M.A.; Özyazici, G.; Ozyazici, M.A.; Erman, Murat (Springer, 2021)
    Abiotic stresses (heat, drought, salinity, and heavy metals) are projected to drastically reduce crop yields leading to seriously jeopardizing the food security of increasing population across the globe. Plant growth ...
  • Effects of Acute Organophosphorus Poisoning on Function of Peripheral Nerves: A Cohort Study 
    Jayasinghe, S.S.; Pathirana, K.D.; Buckley, Nick A. (Plos One, 2012-11-20)
    Background: Following acute organophosphorus (OP) poisoning patients complain of numbness without objective sensory abnormalities or other features of OP induced delayed polyneuropathy. The aim of this study was to measure ...
  • Elevated CO2 in Combination with Heat Stress Influences the Growth and Productivity of Cereals: Adverse Effect and Adaptive Mechanisms 
    Sabagh, Ayman El; Hossain, Akbar; Islam, Mohammad Sohidul; Ahmed, Sharif; Raza, Ali; Iqbal, Muhammad Aamir; Wasaya, Allah; Ratnasekera, Disna; Arshad, Adnan; Kumari, Arpna; Danish, Subhan; Igboji, Paul Ola; Datta, Rahul; Oksana, Sytar; Milan, Skalický; Brestic, Marian; Singh, Kulvir; Raza, Muhammad Ali; Fahad, Shah (CRC Press, 2021)
    The global picture on climate change has been terrifying. Apart from the controversial ozone layer depletion, there is increased radiation, global warming, incidences of excessive or sparse rainfall, flood, drought, ...

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