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Now showing items 14-33 of 36

Factors affecting the avi-faunal distribution in the three lagoons (Malala, Embillakala and Bundala Lewaya) of Bundala National Park (A Ramsar Wetland) in Sri Lanka

Chandana, E.P.S.; Amarasinghe, N. J. de S.; Samayawardhena, L.A. (University of Ruhuna, Matara, Sri Lanka, 2008-09)

Bundala National Park, covering an area of 6216 ha, is located about 250 Km Southeast of Colombo, in the Hambantota District. The shallow brackish water lagoons located within the park - Koholankala (390 ha), Malala (650 ...
Habitat quality and climate variability determine odonate species diversity and distribution patterns in selecte...

Sandamini, P.M.M.A; Gunarathna, S.D.; Chandana, E.P.S. (Academia, 2019-07)

The present study was conducted to reveal the odonate diversity and distribution patterns in selected habitats with reference to habitat quality and climate variability in order to determine the conservation status of ...
Immunity and the role of selected plants as immunomodulators: a review

Chandana, E.P.S. (University of Ruhuna, 2016-09-28)

The immune system is an incredible constellation of cells, tissues, organs and molecules that provides protection against a wide spectrum of pathogens and particles keeping us healthy within the challenging microbial ...
Immunostimulative eff ects of Cyperus rotundus, Alpinia calcarata, Solanum surattense, Clerodendrum infortunatum and Croton laccifer extracts combination on cyclophosphamideinduced immunosuppression in rats

Chandana, E.P.S.; Kithmini, K.K.A.; Gunasekara, T.D.K.S.C. (University of Ruhuna, Matara, Sri Lanka, 2015-06-26)

The present work was undertaken to validate the combinatorial effect of the ethanol extractions of rhizomes of Cyperus rotundus Linn. (“Kalanduru”) and Alpinia calcarata Rosc. (“Heen Araththa”), and root barks of Solanum ...
An Investigation of the Effects of Low Concentrations of Chlorpyrifos on Epididymal Sperm Mutation in Rats

De Silva, W.A.J.P.; Deepananda, K.H.M.A.; Chandana, E.P.S.; Peiris, L.D.C.; Samayawardhena, L.A. (Sri Lanka Association for the Advancement of Science, Colombo, 2001-11-26)

The present study investigated effects of extremely low concentrations of Chlorpyrifos (Pyrimec) to reproductive structure and function of male rats. First, a group o f animals (4 groups; n=10) were given oral dose of ...
Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice

Chandana, E.P.S.; Maeda, Yasuhiro; Ueda, Akihiko; Kiyonari, Hiroshi; Oshima, Naoko; Yamamoto, Mako; Kondo, Shunya; Oh, Junseo; Takahashi, Rei; Yoshida, Yoko; Kawashima, Satoshi; Alexander, D.B; Kitayama, Hitoshi; Takahashi, Chiaki; Tabata, Yasuhiko; Matsuzaki, Tomoko; Noda, Makoto (BioMed Central, 2010)

Developmental angiogenesis proceeds through multiple morphogenetic events including sprouting, intussusception, and pruning. Mice lacking the membrane-anchored metalloproteinase regulator Reck die in utero around embryonic ...
Localization of the membrane-anchored MMP-regulator RECK at the neuromuscular junctions

Kawashima, Satoshi; Imamura, Yukio; Chandana, E.P.S.; Noda, Toru; Takahashi, Rei; Adachi, Eijiro; Takahashi, Chiaki; Noda, Makoto (Blackwell Publishing Ltd, 2008)

Nerve apposition on nicotinic acetylcholine receptor clusters and invagination of the post-synaptic membrane (i.e. secondary fold formation) occur by embryonic day 18.5 at the neuromuscular junctions (NMJs) in mouse ...
A note on bird–habitat relationship in Kirala Kele, Sri Lanka

Samarasekara, W.G.K.H.; Chandana, E.P.S.; Amarasinghe, N.J.de S. (Sri Lankan Journal Online, 2013)
Notes on Lesser Whistling Duck and Other Aquatic Birds in “Kirala Kele” Sanctuary, Matara, Sri Lanka

De Silva, B.C.J.; Gayathri, R.H.W.; Nilmini, N.H.H.M.; Pathum, S.A.M.; Chathuranga, L.S.W.D.; Mahesh B. R., Ranasinghage; Amarasinghe, N.J.De S.; Chandana, E.P.S. (American Institute of Science, 2015-07-23)

Protecting ecosystems in the vicinity of rapidly urbanizing areas requires continuous monitoring and assessment. “Kirala Kele” sanctuary located in Matara city limits of southern Sri Lanka is a well known bird habitat. ...
Occupational exposure levels of Glyphosate among vegetable farmers in Nuwara Eliya, Sri Lanka: A Enzyme-linked Immunosorbent Assay

Eakanayake, E.M.D.V.; Thakshila, W.K.G.; Nishshanka, K.M.; Senawirathne, K.A.A.S.; Perera, H.A.S.D; Gunasekara, T.D.K.S.C.; Asanthi, H.B.; Jayasumana, C.; Chandana, E.P.S.; Abdul, K.S.M.; De Silva, P.M.C.S . (Department of Forestry and Environmental Science, University of Sri Jayewardenepura, Sri Lanka, 2015-10)

Glyphosate (GLY) is a non-selective weedicide widely used by vegetable farmers in Nuwara Eliya (NE), Sri Lanka. It has been recently declared as carcinogenic and induces nephrotoxicity in rat models. Poor weedicide ...
Occupational heat exposure alone may not explain chronic kidney disease of uncertain aetiology (CKDu) in Sri Lanka

De Silva, P. M.C.S.; Ekanayake, E.M.D.V.; Gunasekara, T.D.K.S.C.; Thakshila, W.A.K.G; Sandamini, P.M.M.A.; Abeysiriwardhana, P.A.; Nishara, K.G.D.; Harishchandra, Akila; De Silva, P.H.C.; Siribaddana, Nipuna; Chandana, E.P.S.; Jayasinghe, S.S; Siribaddana, Sisira; Jayasundara, Nishad (Research Square, 2022-05-16)

Chronic kidney disease of uncertain aetiology (CKDu) is an emerging health concern in tropical farming communities. The role ofoccupational heat exposure as a potential driver of CKDu remains debated. Our study examines ...
Occupational herbicide exposure may induce Kidney injury molecule I (KIM I) and Neutrophil Gelatinase-Associated Lipocalin (NGAL) levels in sugarcane farmers in rural Sri Lanka

Eakanayake, D.V.; Abdul, K.S.M.; Thakshila, W.A.K.G.; Asanthi, H.B; Jayasumana, Channa; Jayasinghe, S.S.; Chandana, E.P.S.; Siribaddana, S.H.; De Silva, M.C.S. (International Society for Environmental Epidemiology, 2018-02-01)

Extensive use of herbicides is common among agriculture workers in Sri Lanka (SL). Recent studies hypothesized the role of agrochemicals in the development of mysterious chronic kidney disease termed as CKDu. Paraquat ...
Occupational Paraquat exposure among sugarcane and vegetable farmers in Sri Lanka: A case study

Abdul, K.S.M.; Ekanayake, D.V.; Gunasekara, T. D. K. S. C.; Perera, H.A.S.D.; De Siva, B.C.J.; Jayasumana, C.; Chandana, E.P.S.; Jayasinghe, S.S.; De Silva, P.M.C.S. (Institute of Biology, Sri Lanka, 2015-09)

Paraquat (1, 1 – dimethyl -4, 4- bipyridylium dichloride) is a contact herbicide, predominantly used in Sri Lanka. Despite the imposed ban in agriculture sector, Paraquat usage was seen among sugarcane farmers in Pelawatta ...
Pesticide Use, Handling and Awareness among Rural Farmers in Sri Lanka: Implications on Emerging Chronic Kidney Disease of Uncertain Etiology (CKDu)

Thakshila, W.A.K.G.; Ekanayake, E.M.D.V.; Abdul, K.S.M.; Samanmali, M.A.G.D.; Jayasinghe, S.S .; Jayasumana, C.S.; Chandana, E.P.S.; Siribaddana, S.H.; De Silva, P.M.C.S. (General Sir John Kotelawala Defence University, 2018)

Agrochemical exposure has been considered as the main risk factor of Chronic Interstitial Nephritis in Agricultural Communities (CINAC) in Sri Lanka. Poor awareness and agrochemical handling practices could lead ...
Physico-chemical and biological environment of Malala lagoon at Bundala National park under overwhelming fresh water influence

Chandana, E.P.S.; Ravindra, R.; Lasanthi, P.; De S, Amarasinghe N. J.; Peiris, L.D.C.; Samayawardhena, L.A. (Sri Lanka Association for the Advancement of Science, Colombo, 2001-11-26)

Bundala National Park situated in Southern Sri Lanka is the only Ramsar wetland system in the country. Malala lagoon, the largest water body in Bundala National Park is a very productive ecosystem that is demarcated by ...
A preliminary study on the toxic effects of an emerging detergent (Prinso) on rat skin

Dayasiri, P.B.I.A.K; Chandana, E.P.S. (Faculty of Science, University of Jaffna, 2011-10-11)

Toxic effects of household detergents on human skin have been reported previously. Recently emerged detergent “PRINSO” is extensively gaining popularity in many areas of Sri Lanka. “PRINSO” is also sold under other ...
RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity

Muraguchi, Teruyuki; Takegami, Yujiro; Ohtsuka, Toshiyuki; Kitajima, Shunsuke; Chandana, E.P.S.; Omura, Akira; Miki, Takao; Takahashi, Rei; Matsumoto, Naoya; Ludwig, Andreas; Noda, Makoto; Takahashi, Chiaki (Nature Publishing Group, 2007-06-10)

We report that during cortical development in the mouse embryo, reversion-inducing cysteine-rich protein with Kazal motifs (RECK) critically regulates Notch signaling by antagonizing the ectodomain shedding of Notch ligands, ...
The Reck tumor suppressor protein alleviates tissue damage and promotes functional recovery after transient cerebral ischemia in mice

Wang, Huan; Imamura, Yukio; Ishibashi, Ryota; Chandana, E.P.S.; Yamamoto, Mako; Noda , Makoto (Blackwell Publishing Ltd, 2010)

The extracellular matrix (ECM) is important for both structural integrity and functions of the brain. Matrix metalloproteinases (MMPs) play major roles in ECM-remodeling under both physiological and pathological conditions. ...
Significance of Mammalian Epididymal Morphology in Sperm Maturation

Chandana, EPS; Samayawardhena, LA; Peiris, LDC (Sri Lanka Association for the Advancement of Science, Colombo, 2000-11-27)

The mammalian epididymis is a highly convoluted tubule, which can be divided into several regions depending either on its functional capability or its morphology, Epididymal duct is narrow and long. It is lined by a ...
Some Hydrographic aspects of Koggala Lagoon with preliminary results on distribution of the marine bivalve Saccostrea forskalli : pre-tsunami status

Gunawickrama, K.B.S.; Chandana, E.P.S. (Sri Lanka journals online, 2006-09)

Selected hydrographic parameters of Koggala lagoon over a period of four months in 2002- 2003 are reported together with the preliminary results on the distribution of a marine bivalve within lagoon. Such data prior to ...

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