Scholarly Publications of Academic Members: Recent submissions

Now showing items 21-40 of 1956

Methicillin-resistant Staphylococcus Aureus: Prevalence of and Risk Factors Associated with Colonization of Patients on Admission to the Teaching Hospital, Karapitiya

Kurukulasooriya, R.; Tillekeratne, L.G.; Wijayaratne, W.M.D.G.B.; Bodinayake, C.K.; De Silva, A.D.; Nicholson, B.P.; Ostbye, T.; Woods, Christopher W.; Nagahawatte, A. (University of Ruhuna, 2018-12-30)

Methicillin-resistant Staphylococcus aureus (MRSA) causes a substantial burden of community-acquired and nosocomial infection. Prior colonization with MRSA is a recognized risk factor for MRSA infection. The study aimed ...
Evaluation of the WHO 2009 Classification for Diagnosis of Acute Dengue in a Large Cohort of Adults and Children in Sri Lanka During a Dengue-1 Epidemic

Bodinayake, C.K.; Tillekeratne, L.G.; Nagahawatte, A.; Devasiri, V.; Arachchi, W.K.; Strouse, John J.; Sessions, October M.; Kurukulasooriya, R.; Uehara, Anna; Howe, Shiqin; Xin Mei Ong; Tan, Sharon; Chow, Angelia; Tummalapalli, P.; De Silva, A.D.; Ostbye, T.; Woods, Christopher W.; Gubler, Duane J.; Reller, Megan E. (Public Library of Science (PLOS), 2018-02-09)

Background Dengue is a leading cause of fever and mimics other acute febrile illnesses (AFI). In 2009, the World Health Organization (WHO) revised criteria for clinical diagnosis of dengue. Methodology/Principal ...
Respiratory Viral Infection: An Underappreciated Cause of Acute Febrile Illness Admissions in Southern Sri Lanka

Tillekeratne, L.G.; Bodinayake, C.K.; Simmons, R.; Nagahawatte, A.; Devasiri, V.; Arachchi, W.K.; Vanderburg, Sky; Kurukulasooriya, R.; De Silva, A.D.; Ostbye, T.; Reller, Megan E.; Woods, Christopher W. (The American journal of tropical medicine and hygiene, 2018-12-26)

he contribution of respiratory viruses to acute febrile illness (AFI) burden is poorly characterized. We describe the prevalence, seasonality, and clinical features of respiratory viral infection among AFI admissions in ...
Point-prevalence Study of Antimicrobial Use in Public Hospitals in Southern Sri Lanka Identifies Opportunities for Improving Prescribing Practices

Tianchen Sheng; Wijayaratne, W.M.D.G.B.; Dabrera, T.M.; Drew, Richard J.; Nagahawatte, A.; Bodinayake, C.K.; Kurukulasooriya, R.; Ostbye, T.; Nagaro, Kristin J.; De Silva, C.; Ranawakaarachchi, H.; Sudarshana, A.T.; Anderson, Deverick J.; Weerasinghe, Christopher W.; Tillekeratne, L.G. (Cambridge University Press, 2019-02-01)

A point-prevalence study of antimicrobial use among inpatients at 5 public hospitals in Sri Lanka revealed that 54.6% were receiving antimicrobials: 43.1% in medical wards, 68.0% in surgical wards, and 97.6% in intensive ...
Extrapulmonary Tuberculosis Presenting as a Dumbbell Tumour of the Chest Wall

Kariyawasam, A.G.T.A.; Fonseka, C.L.; Rasnayake, D.; Singhapura, S.D.A.L.; Sanjeewa, A.D.S.; Hewavithana, J.; Masakorala, N.D.; Dahanayake, N.J.; Bodinayake, C.K. (Galle Medical Association, 2019-03-01)

Tuberculosis gives rise to a significant impact on the healthcare burden in tropical countries where it can present in a variety of ways. The commonest site of tuberculous infection is the lung, while extra-pulmonary ...
Use of Clinical Algorithms and Rapid Influenza Testing to Manage Influenza-like Illness: a Cost-effectiveness Analysis in Sri Lanka.

Tillekeratne, L.G.; Bodinayake, C.K.; Nagahawatte, A.; Kurukulasooriya, R.; Orlando, Lori A.; Simmons, Ryan A.; Park, Lawrence P.; Woods, Christopher W.; Reed, Shelby D. (BMJ Publishing Group Ltd., 2019-03-30)

Background Acute respiratory infections are a common reason for antibiotic overuse. We previously showed that providing Sri Lankan clinicians with positive rapid influenza test results was associated with a reduction in ...
Geospatial Analysis of Dengue Emergence in Rural Areas in the Southern Province of Sri Lanka

Mutucumarana, C.P.; Bodinayake, C.K.; Nagahawatte, A.; Devasiri, V.; Kurukulasooriya, R.; Anuradha, T.; De Silva, A.D.; Janko, Mark M.; Ostbye, T.; Gubler, Duane J.; Woods, Christopher W.; Reller, Megan E.; Tillekeratne, L.G.; Lantos, Paul M. (Oxford University Press, 2020-06-01)

Background: Dengue is a major cause of acute febrile illness in Sri Lanka. Dengue has historically been considered an urban disease. In 2012–2013, we documented that acute dengue was surprisingly associated with self- reported ...
Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population

Tillekeratne, L.G.; Suchindran, S.; Ko, Emily R.; Petzold, Elizabeth A.; Bodinayake, C.K.; Nagahawatte, A.; Devasiri, V.; Kurukulasooriya, R.; Nicholson, B.P.; McClain, Micah T.; Burke, Thomas W.; Tsalik, Ephraim L.; Henao, Ricardo; Ginsburg, Geoffrey S.; Reller, Megan E.; Woods, Christopher W. (Oxford University Press, 2020-05-26)

Background. Pathogen-based diagnostics for acute respiratory infection (ARI) have limited ability to detect etiology of illness. We previously showed that peripheral blood-based host gene expression classifiers accurately ...
Point-prevalence Survey of Outpatient Antibiotic Prescription at a Tertiary Medical Center in Sri Lanka: Opportunities to Improve Prescribing Practices for Respiratory Illnesses

Zhang, Helen L.; Bodinayake, C.K.; Wijayaratne, W.M.D.G.B.; Jayatissa, P.; Piyasiri, B.; Kurukulasooriya, R.; Tianchen Sheng; Nagahawatte, A.; Woods, Christopher W.; Tillekeratne, L.G. (BioMed Central (BMC), 2021-01-21)

Background: Inappropriate antibiotic use is linked to the spread of antimicrobial resistance worldwide, but there are limited systemic data on antibiotic utilization in low- and middle-income countries. The purpose of ...
Barriers to Implementing Antimicrobial Stewardship Programs in Three Low- and Middle-income Country Tertiary Care Settings: Findings from a Multi-site Qualitative Study

Rolfe Jr, Robert; Kwobah, Charles; Muro, Florida; Ruwanpathirana, A.; Lyamuya, Furaha S.; Bodinayake, C.K.; Nagahawatte, A.; Piyasiri, B.; Tianchen Sheng; Bollinger, J.; Chi Zhang; Truls Ostbye; Ali, Shamim; Drew, R.; Kussin, P.; Anderson, Deverick J.; Woods, Christopher W.; Watt, Melissa H.; Mmbaga, Blandina T.; Tillekeratne, L.G. (Springer Nature, 2021-03-25)

Background: Antimicrobial resistance has been named as one of the top ten threats to public health in the world. Hospital-based antimicrobial stewardship programs (ASPs) can help reduce antimicrobial resistance. The purpose ...
Colonization with Multidrug-resistant Enterobacteriaceae Among Infants: an Observational Study in Southern Sri Lanka

Meredith, Hannah R.; Kularathna, S.; Nagaro, Kristin; Nagahawatte, A.; Bodinayake, C.K.; Kurukulasooriya, R.; Wijesingha, N.; Harden, Lyndy B.; Piyasiri, B.; Hammouda, Amr; Wiegmann, Brian M.; Nicholson, B.P.; Joyce, Maria; Woods, Christopher W.; Van Vliet, Arnoud H. M.; Thakur, Siddhartha; Tillekeratne, L.G. (Springer Nature, 2021-04-30)

Background The timing of and risk factors for intestinal colonization with multidrug-resistant Enterobacteriaceae (MDRE) are still poorly understood in areas with high MDRE carriage. We determined the prevalence, timing, ...
The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood

Tsalik, Ephraim L.; Fiorino, Cassandra; Aqeel, Ammara; Liu, Yiling; Henao, Ricardo; Ko, Emily R.; Burke, Thomas W.; Reller, Megan E.; Bodinayake, C.K.; Nagahawatte, A.; Arachchi, W.K.; Devasiri, V.; Kurukulasooriya, R.; McClain, Micah T.; Woods, Christopher W.; Ginsburg, G.S.; Tillekeratne, L.G.; Schughart, Klaus (Frontiers Media SA , 2021-10-27)

Viruses cause a wide spectrum of clinical disease, the majority being acute respiratory infections (ARI). In most cases, ARI symptoms are similar for different viruses although severity can be variable. The objective of ...
Knowledge, Perceptions, and Attitudes Regarding Antibiotic Use for Lower Respiratory Tract Infections: Insights from Patients in Sri Lanka.

Van Melle, David T.; Asbroek, Guus Ten; Rolfe, R.; Vanderburg, Sky; Abeysinghe, Y. W.; Halloluwa, C.; Zhang, Helen L.; Ostbye, T.; Kurukulasooriya, R.; Tianchen Sheng; Kanchana, S.; Wijayaratne, W.M.D.G.B.; Bodinayake, C.K.; Nagahawatte, A.; Watt, Melissa H.; Woods, Christopher W.; De Silva, P.V.; Tillekeratne, L.G. (American Society of Tropical Medicine and Hygiene, 2021-09-27)

Antibiotic resistance is an emerging global public health threat. One of the main drivers of this threat is the inappropriate use of antibiotics. In Sri Lanka, antibiotic consumption is increasing, but little is known ...
Outcomes Among Children and Adults at Risk of Severe Dengue in Sri Lanka: Opportunity for Outpatient Case Management in Countries with High Disease Burden

Bodinayake, C.K.; Nagahawatte, A.; Devasiri, V.; Dahanayake, N.J.; Wijayaratne, W.M.D.G.B.; Weerasinghe, N.P.; Premamali, M.; Tianchen Sheng; Nicholson, B.P.; Ubeysekera, H.A.; Kurukulasooriya, R.; De Silva, A.D.; Ostbye, T.; Woods, Christopher W.; Tillekeratne, L.G. (Public Library of Science (PLOS), 2021-12-28)

Background Healthcare systems in dengue-endemic countries are often overburdened due to the high number of patients hospitalized according to dengue management guidelines. We systematically evaluated clinical outcomes ...
Opportunities for Improving Antimicrobial Stewardship: Findings from a Prospective, Multi-Center Study in Three Low- or Middle-Income Countries

Muro, Florida J.; Lyamuya, Furaha S.; Kwobah, C.; Bollinger, J.; Bodinayake, C.K.; Nagahawatte, A.; Piyasiri, B.; Kurukulasooriya, R.; Ali, Shamim; Mallya, R.; Rolfe Jr, R.; Ruwanpathirana, A.; Tianchen Sheng; Østbye, T.; Drew, R.; Kussin, P.; Woods, Christopher W.; Anderson, Deverick J.; Mmbaga, Blandina T.; Tillekeratne, L.G. (Frontiers Media SA, 2022-04-25)

Background: To develop effective antimicrobial stewardship programs (ASPs) for low- and middle-income countries (LMICs), it is important to identify key targets for improving antimicrobial use. We sought to systematically ...
A Practical Approach to Lung Ultrasound Training in Sri Lanka

Vanderburg, Sky; Kodikara, I.; Tharakan, Anna; Tianchen Sheng; Gallis, John A.; Sellathurai, M.; Bodinayake, C.K.; Nagahawatte, A.; Wijayaratne, W.M.D.G.B.; Woods, Chris W.; Tillekeratne, L.G.; Riviello, Elisabeth D. (ATS Scholar, 2023-02-28)
Influenza Vaccination Implementation in Sri Lanka: A Cost-Effectiveness Analysis

Neighbors, Coralei E.; Myers, Evan R.; Weerasinghe, N.P.; Wijayaratne, W.M.D.G.B.; Bodinayake, C.K.; Nagahawatte, A.; Tillekeratne, L.G.; Woods, Christopher W. (Vaccine, 2023-05-03)

nfluenza causes an estimated 3 to 5 million cases of severe illness annually, along with substantial morbidity and mortality, particularly in low- and middle-income countries (LMICs). Currently, Sri Lanka has no influenza ...
Comprehensive Diagnostic Testing Identifies Diverse Aetiologies of Acute Febrile Illness Among Hospitalised Children and Adults in Sri Lanka: a Prospective Cohort Study

Bodinayake, C.K.; Nagahawatte, A.; Devasiri, V.; Arachichi, W.K.; Kurukulasooriya, R.; Tianchen Sheng; Nicholson, B.P.; Ostbye, T.; Reller, Megan; Woods, Christopher W.; Tillekeratne, L.G. (BMJ Public Health, 2023-07-31)

Introduction Acute febrile illness (AFI) is a common cause of hospital admissions in tropical settings. Identifying AFI aetiology is essential for guiding clinicians’ diagnoses and developing diagnostic and management ...
Prevalence and Predictors of Antibiotic Prescription Among Patients Hospitalized with Viral Lower Respiratory Tract Infections in Southern Province, Sri Lanka

Medrano, P.G.; Weerasinghe, N.; Nagahawatte, A.; Vanderburg, Sky; Park, Lawrence P.; Wijayaratne, W.M.D.G.B.; Devasiri, V.; Dilshan, B.; Tianchen Sheng; Kurukulasooriya, R.; Anderson1, J.; Nicholson, B.P.; Woods, Christopher W.; Bodinayake, C.K.; Tillekeratne, L.G. ( PLoS one, 2024-06-11)

Background: Antimicrobial overprescription is common for lower respiratory tract infections (LRTI), as viral and bacterial infections generally present with similar clinical features. Overprescription is associated with ...
Prevalence and Molecular Epidemiology of Methicillin-resistant Staphylococcus Aureus in Livestock Farmers, Livestock, and Livestock Products in Southern Sri Lanka: A One Health Approach

Kurukulasooriya, M.R.P.; Tillekeratne, L.G.; Wijayaratne, W.M.D.G.B.; Bodinayake, C.K.; Dilshan, U.H.B.Y.; De Silva, A.D.; Nicholso, B.P.; Østbye, T.; Woods, C.W. (Elsevier, 2024-11-29)

Methicillin-resistant Staphylococcus aureus (MRSA) colonization can lead to subsequent severe infections. Unlike community and hospital-associated types, Livestock-associated MRSA (LA-MRSA) transmits to humans through direct ...

Now showing items 21-40 of 1956

Search DSpace

Advanced Search

Browse

All of DSpace
This Community
- By Issue Date
- Authors
- Titles
- Subjects

Recently added

Scholarly Publications of Academic Members: Recent submissions

Search DSpace

Browse

All of DSpace

This Community

My Account