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Now showing items 1-20 of 260

Serotonin inhibits voltage-gated sodium current by cyclic adenosine monophosphate-dependent mechanism in bullfrog taste receptor cells

Imendra, K.G.; Imendra, R.; Miyamoto, T.; Okada, Y.; Sato, T. (Elsevier, 2000-11-24)

We have investigated the effect of 5-hydroxytryptamine (serotonin) (5-HT) on the membrane properties of bullfrog taste receptor cells (TRCs) using patch-clamp technique. External application of 5-HT reversibly suppressed ...
Serotonin differentially modulates the electrical properties of different subsets of taste receptor cells in bullfrog

Imendra, K.G.; Miyamoto, Takenori; Okada, Yukio; Toda, Kazuo (Wiley - Blackwell, 2002-09-19)

Serotonin (5-hydroxytryptamin, 5-HT) is localized in taste bud cells of vertebrates. Effects of the external application of 5-HT on the membrane currents of frog taste receptor cells (TRCs) were investigated using patch-clamp ...
Biophysical properties of voltage-gated Na+ channels in frog parathyroid cells and their modulation by cannabinoids

Okada, Yukio; Imendra, K.G.; Miyazaki, Toshihiro; Hotokezaka, Hitoshi; Fujiyama, Rie; Zeredo, Jorge L.; Miyamoto, Takenori; Toda, Kazuo (The Company of Biologists (United Kingdom), 2005-12-15)

The membrane properties of isolated frog parathyroid cells were studied using perforated and conventional whole-cell patch-clamp techniques. Frog parathyroid cells displayed transient inward currents in response ...
A Calcium-Receptor Agonist Induces Gustatory Neural Responses in Bullfrogs

Okada, Yukio; Imendra, K.G.; Miyazaki, Toshihiro; Hotokezaka, Hitoshi; Fujiyama, Rie; Zeredo, Jorge L.; Toda, Kazuo (Springer Link, 2007-07-17)

The effect of calcium-sensing receptor (CaR) agonists on frog gustatory responses was studied using glossopharyngeal nerve recording and whole-cell patch clamp recording of isolated taste disc cells. Calcimimetic NPS R-467 ...
Effects of Gymnema lactiferum leaf on glycemic and lipidemic status in type 2 diabetic subjects

Bandara, Thushari; Rokeya, Begum; Khan, Sakina; Ali, Liaquat; Ekanayake, Sagarika; Jansz, Errol R.; Balasubramanium, Kandiah (Bangladesh Pharmacological Society, 2008-10-04)

Gymnema lactiferum var. lactiferum is a climber distributed in many South Asian countries. It is reported that the diabetic patients in Sri Lanka use G. lactiferum leaves as a treatment for diabetes. However, scientific ...
High Extracellular Ca2+ Stimulates Ca2+-Activated Cl− Currents in Frog Parathyroid Cells through the Mediation of Arachidonic Acid Cascade

Okada, Yukio; Imendra, K.G.; Miyazaki, Toshihiro; Hotokezaka, Hitoshi; Fujiyama, Rie; Toda, Kazuo (Public Library of Science, 2011-04-29)

Elevation of extracellular Ca2+ concentration induces intracellular Ca2+ signaling in parathyroid cells. The response is due to stimulation of the phospholipase C/Ca2+ pathways, but the direct mechanism responsible for ...
Bioactivity of cinnamon with special emphasis on diabetes mellitus: A review

Bandara, Thushari; Uluwaduge, Inoka; Jansz, E.R. (Informa UK, Ltd., 2011-10-19)

Cinnamon is the oldest spice and has been used by several cultural practices for centuries. In addition to its culinary uses, cinnamon possesses a rising popularity due to many stated health benefits. Out of the large ...
Effect of morphological preservation artifacts on the quality of immuno histochemical staining forER and Her-2

Peiris, H.H.; Mudduwa, L.K.B.; Liyanage, T.; Ranasinghe, J.G.S. (Galle Medical Journal, 2013)

Introduction: The most commonly encountered morphological preservation artifacts in the histological assessment of breast cancer include retraction of tumour cell clusters from the stroma, cytoplasmic retraction and ...
Pattern of clinically recognisable congenital malformations in babies born in a tertiary referral centre in Sri Lanka

Fernando, S.; Bandara, T.; Sathanantharajah, R.; Withanaarachchi, K. (The Sri Lanka Medical Association, 2014)

Objectives To record incidence, pattern and prevalence of risk factors of congenital malformations (CM) in live new born babies at a Teaching Hospital in Sri Lanka. Methods All newborn babies delivered over a period ...
Prevalence of Musculoskeletal Pains among three wheel drivers in Galle Municipality area of Galle District in Sri Lanka

Gamage, M.W.K.; Warnakulasuriya, S.S.P. (General Sir John Kotelawala Defence University, 2014)

The number of three wheelers on the roads in every part of the country has increased during past two decades in Sri Lanka. Three wheel driving is one of the common options for thousands of youth who dropped out from schools. ...
Current infant feeding practices and impact on growth in babies during the second half of infancy

Bandara, T.; Hettiarachchi, M.; Liyanage, C.; Amarasena, S. (The British Dietetic Association Ltd., 2014-06-30)

Background: Sri Lanka has made remarkable improvements in health, social and educational indices. However, child malnutrition exists as a significant health problem. Infant feeding indicators have not reached expected ...
A Study on Accuracy and Completeness of Handwritten Outpatient Prescriptions in Sri Lanka

De Silva, K.I.M.; Sakeena, M.H.F.; Parakramawansha, K.P.R.C. (Peradeniya University International Research Sessions, University of Peradeniya, Sri Lanka, 2014-07-14)

Medication errors can occur in all stages of the medication process: prescribing, dispensing, administration, monitoring and documentation. Among them most of the prescription errors occur in the prescription writing ...
The Effects of Lipid Peroxidation and Storage Conditions on Keeping Quality of Snake Head Fish (Channastriata)

Ramanayake, R.M.T.M.; Sakai, T.; Munasinghe, D.M.S. (University of Peradeniya, 2014-12-15)

The experiment was conducted to determine the progression of lipid peroxidation and the effects of it on Snake head fish (Channastriata) stored at -100C for 28 days. Fish were harvested from Victoria reservoir and ...
Choice of antidote methionine usage on patients with acute paracetamol poisoning in the specialized toxicology unit in Sri Lanka

Pathiraja, V.M.; Gawarammana, I.B.; Dawson, A.H. (Asia Pacific Association of Medical Toxicology 14th International Scientific Conference, Perth, Australia, 2015)

Objective: This study was carried out to evaluate the choice of antidote, oral methionine, 4 doses of 2'59 q4h or intiavenous N acetylcysteine (iv NAC) 3OOmg/kg over 20 hours in the treatment of acute paracetamol ...
Changes in the demographic pattern of animal rabies in the Central province of Sri Lanka

Ramanayake, R.M.T.M.; Amarasiri, P.G.I.D.; Karawita, A.C.; Jayaweera, W.R.; Obayashi, Y.; Hiko, T.; Gunawardena, G.S.P. De S. (2015)

Rabies is a fatal zoonotic viral disease of public health importance endemic in Sri Lanka. Poor surveillance, underreporting in many developing countries and frequent misdiagnosis of rabies have lead to underestimation ...
Sensitivity and specificity of the Negri body test using Sellers’ stain in the diagnosis of rabies in dogs

Ramanayake, R.M.T.M.; Amarasiri, P.G.I.D.; Karawita, A.C.; Jayaweera, W.R.; Obayashi, Y.; Hiko, T.; Gunawardena, G.S.P. De S. (2015)

Rabies is an invariably fatal zoonotic viral disease which infects all mammalian species. Dog rabies is the main source of infection for human disease. Confirmation of rabies infection requires laboratory testing of ...
Metal-Enhanced Fluorescence of Dye-Doped Silica Nano Particles

Gunawardana, K.B.; Green, N.S.; Bumm, L.A.; Halterman, R.L. (Springer, 2015-01-28)

Recent advancements in metal-enhanced fluorescence (MEF) suggest that it can be a promising tool for detecting molecules at very low concentrations when a fluorophore is fixed near the surface of metal nanoparticles. ...
The Deuterium Oxide–to-the-Mother Method Documents Adequate Breast-Milk Intake among Sri Lankan Infants1–4

Bandara, T.; Hettiarachchi, M.; Liyanage, C.; Amarasena, S.; Wong, William W. (Community and International Nutrition, 2015-04-22)

Background: The WHO recommends that exclusive breastfeeding should last up to 6 mo. However, human milk intake of Sri Lankan infants has not been quantified scientifically. Objectives: The objectives of this study were ...
Body composition among Sri Lankan infants by 18O dilution method and the validity of anthropometric equations to predict body fat against 18O dilution

Bandara, T.; Hettiarachchi, M.; Liyanage, C.; Amarasena, S.; Wong, William Wai-Lun (BMC Pediatrics, 2015-05-06)

Background Body composition indicators provide a better guidance for growth and nutritional status of the infants. This study was designed to (1) measure the body composition of the Sri Lankan infants using a reference ...
Risk factors and clinico-pathological profile of Triple Negative Breast Cancer; A comparative study done in southern province of Sri Lanka

Peiris, H.H.; Mudduwa, L.K.B.; Thalagala, N.I.; Jayatilaka, K.A.P.W. (University of Sri Jayewardenepura, 2015-06-11)

Objectives: To compare the risk factors and clinico-pathological features of Triple Negative Breast Cancer (TNBC) and non-TNBC in females in Southern Province of Sri Lanka Methods: This retrospective study included ...

Now showing items 1-20 of 260

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