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Now showing items 1-20 of 121

Acute and Sub- chronic Toxicity of Antihyperglycaemic Leaf Extract of Coccinia Grandis

Attanayake, A.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B.; Pathirana, C. (University of Ruhuna, 2013-03-20)
Acute and Sub-acute Toxicological Evaluation of Barleria Prionitis Linn. in Wistar Albino Rats

Amarasiri, S.S.; Attanayake, A.P.; Mudduwa, L.K.B.; Jayatilaka, K.A.P.W. (Faculty of Science, University of Peradeniya, Sri Lanka, 2023-10-23)

Despite the wide usage of Barleria prionitis Linn. (Acanthaceae) in traditional medicine, controversial findings have been reported on possible toxic effects of the plant. The present study evaluated the acute and sub-acute ...
Acute Pigmented Tubulopathy and Interstitial Nephritis Following Wasp Sting

Gunasekera, W.T.P.; Mudduwa, L.K.B.; Lekamwasam, S. (Galle Medical Association, 2009-07-09)
Adriamycin Induced Nephropathy in Wistar Rats: an in Vivo Model to Screen Nephroprotective Activity of Natural Products

Amarasiri, A.M.S.S.; Attanayake, A.P.; Mudduwa, L.K.B.; Jayatilaka, K.A.P.W. (University of Ruhuna, 2017-02)
Ameliorative Effects of Asparagus Falcatus L and Vetiveria Zizanioides (L) Nash on Carbon Tetrachloride Induced Oxidative Stress in Mice

Hewawasam, R.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B.; Pathirana, C. (National Institute of Science Communication and Policy Research, 2017-07)

The hepatoprotective and antioxidative effects of two aqueous plant extracts, Asparagus falcatus and Vetiveria zizanioides, were determined against carbon tetrachloride (CCl4) induced oxidative stress in mice. Hepatotoxicity ...
Ameliorative Potential of Coccinia Grandis on Hepatic Antioxidant Status in STZ- Diabetic Rats

Attanayake, A.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B.; Pathirana, C. (Galle Medical Association, 2012-02)
Angiomyomatous Hamartoma (AMH) of the Lymph Node; a Rare Cause for Isolated Lymphadenopath

Rojika, K.B.; Wijesiri, T.W.; Liyanage, T.G. (Faculty of Medicine, University of Ruhuna, 2024)

Introduction Angiomyomatous hamartoma is a benign vascular lesion of lymph node with unknown etiology. May represent previous inflammatory process or chronic blockade of lymphatic flow. It is characterized by replacement ...
Animal Models of Chronic Kidney Disease: screening Tool to Investigate Nephroprotective Effects of Natural Products

Amarasiri, S.S.; Attanayake, A.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (IP Innovative Publication Pvt. Ltd, 2018-11)

Animals are used as experimental models to reproduce human diseases. To date, various animal models have been successfully developed by numerous methods to simulate human diseases including chronic kidney disease (CKD). ...
Applicability of Western Protocols in Resource-limited Setting: Real-world data of Long-term Outcome of Intensive Treatment of adult acute mMyeloid Leukaemia in Sri Lanka

Hewamana, S.; Kandabadage, L.; Skandarajah, T.; Pieris, N.; Perera, E.; Harischandra, M.; Wijewickrama, A.; Wickramaratne, K.A.C.; Somasundaram, G.; Srinivasan, V.; Somiah, S.; Jayawardena, P.; Perera, M.; Gunasekera, D.; Jayasinghe, C.; Constantine, G.; Munasinghe, S.; De Silva, C.; Wijesiriwardena, B.; Balawardena, J. (Wiley International, 2021-05-13)

There are no published data on long-term survival and applicability of treatment protocols from developed countries in acute myeloid leukaemia (AML) in Sri Lanka. Eighty-seven AML patients were reviewed; there were 56 newly ...
Appropriateness of Using Patient Data for Calculation of Reference Intervals for Complete Blood Count (CBC) in Elderly Population

Wijewickrama, D.C.; Wickramaratne, K.A.C. (2022-10)
An Aqueous Eextract of Gmelina Arborea: Efficacy and Dose Response on Glucose Tolerance in Alloxan Induced Diabetic Rats.

Attanayake, A.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B.; Pathirana, C. (Ceylon Association for the advancement of science, 2011-12)
Assessing the Validity of the Threefold Conversion between Hemoglobin and Hematocrit for the Determination of Anemia in Pregnancy

Amarasiri, A.M.S.S.; Wickramaratne, K.A.C. (General Sir John Kotelawala Defence University, 2014-08-21)

Introduction: The worldwide prevalence of anemia is higher among pregnant women. Anemic status is determined by the measurement of Hemoglobin (Hb) or Hematocrit (Hct). Hct (%) is usually defined as three times the value ...
Association Between Age at Presentation and Pathological Features of Breast Cancer and its Effect on Survival; a Comparative Study done in Sri Lanka

Peiris, H.; Mudduwa, L.K.B.; Thalagala, N.; Jayatilaka, K.A.P.W. (International Institute for Primary Health Care, 2015-08)

Objective: The young age at presentation of breast can- cer (BC) is an independent prognostic factor of poor survival. Therefore the aim of this study was to deter- mine the association between age at presentation and ...
Association Between Dysglycemia, Body Mass Index and Body Compositions in a Group of Community Dwellers

Silva, E.H.; Wickramatilake, C.M.; Lekamwasam, S.; Mudduwa, L.K.B.; Ubayasiri, R.A. (Faculty of Allied Health Science, Faculty of Medicine, University of Ruhuna, Sri Lanka, 2019-12)

Background: Obesity is a leading cause of diabetes mellitus. There are no studies examining the relationship between Glycated haemoglobin (HbA1c) and components of body fat among Sri Lankans. Objectives: The objective of ...
Association Between Serum Vitamin D and Body Mass Index and Fat Mass in a Group of Community Dwellers

Silva, E.H.; Wickramatilake, C.M.; Lekamwasam, S.; Mudduwa, L.K.B.; Ubayasiri, R.A. (University of Ruhuna, Sri Lanka, 2019-03)

Enter an abstract of maximum 300 words here (English: Times New Roman, 10pt; Sinhala: Unicode-Iskoola Pota ,10pt). Introduction Vitamin D insufficiency is linked with obesity which leads to many health problems including ...
Association of Bone Mineral Density and Content (bmd/bmc) with Total Body Fat and Lean Masses Among Patients with Chronic Renal Failure Attending Teaching Hospital, Karapitiy

Silva, E.H.; Wickramatilake, C.M.; Lekamwasam, S.; Mudduwa, L.K.B.; Ubayasiri, R.A. (2018-12)

Introduction and objective Interaction between three major body compartments; lean, fat and bone masses is essential for the maintenance of optimum bodily functions. This interaction is disturbed by many factors such as ...
Awareness of Breast Cancer Among Females with Breast Diseases

Mudduwa, L.K.B.; Wijesinghe, C.J. (Galle Medical Association, 2009-07-29)

Introduction: Breast cancer is the commonest cancer among females. Women need to be aware about the clinical symptoms and course of the disease to increase the chances of early detection of breast cancer and thereby to ...
Beneficial Effects on Glycaemic Control and Serum Lipid Profile by Coccinia Grandis (Cucurbitaceae) Leaf Extract in Alloxan Induced Diabetic Rats

Attanayake, A.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B.; Pathirana, C. (Ceylon Association for the Advancement of Science, 2012-02)
Cardioprotective Potential of Murraya koenigii (L.) Spreng. Leaf Extract Against Doxorubicin-Induced Cardiotoxicity in Rats

Sewwandi, J.A.N.; Hewawasam, R.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (Hindawi, 2020-03-16)

Dose-dependent cardiotoxicity of doxorubicin may lead to irreversible congestive heart failure. Although multiple mechanisms are involved, generation of free radicals is the most commonly postulated mechanism. Therefore, ...
Characterization of Anaemia in Patients with CKD at the National Institute for Nephrology Dialysis and Transplantation

Riyas, F.R.; Wickramaratne, K.A.C.; Bandaranayaka, K.; Chathuranga, G.; Wijesundara, C. ("Faculty of Medical Sciences, University of Sri Jayewardenepura. ", 2019-10)

Background: Chronic kidney disease (CKD) is the third leading cause of mortality and affect 5-10 million people worldwide. Decreased production of erythropoietin (EPO) caused by renal damage leads to anaemia in CKD ...

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