Citation:Hettihewa, L.M., Gunasekera, S.W., Jayasinghe, S.S., Palangasinghe, S., Weerarathna, T.P. and Kotapola, I., 2009. Lipid abnormalities in type 2 diabetes mellitus patients in Sri Lanka. Galle Medical Journal, 12(1), pp.1–4. DOI: http://doi.org/10.4038/gmj.v12i1.1076
Date:2009-09-25
Abstract:
Background & Objective: Previous studies
suggest that the prevalence of dyslipidaemia in
type 2 diabetes is high with respect to the general
population. But data related to the prevalence of
dyslipidaemia in diabetic population is limited in
Sri Lanka. This study was planned to identify the
prevalence of abnormalities in lipid profile
among type 2 diabetic population.
Methods: All subjects were studied for their
quantitative lipid abnormalities after an
overnight fast. Their anthropometric indices were
measured and fasting blood sample was collected
for glucose and lipids determinations.
Results: Mean value of BMI was 23.67 ± 0.58
2
kg/m and FBS was 179.3 ± 9.98 mg/dL. There
were 67% patients with high TC levels and 44%
of patients with high triglyceride levels.
Increased LDL levels were found in 51% of
patients and 19% of patients had lower HDL
levels both in males & females. We found that
65% of patients had more than one risk factor in
lipid profiles. Further, 74% of patients had
combination of significantly high TC and low
HDL levels.
Interpretation & Conclusion: Contrary to the
previous research findings, total cholesterol is the
most common lipid abnormality in type 2
diabetics. Considering our different prevalence
rates of dyslipidaemia among diabetic patients,
we strongly suggest to promote investigations
related to the effects of abnormalities of total
cholesterol on the development of insulin
resistance, the major causative factor for type 2
diabetes.
