Waspergillamide A, a Nitro depsi-Tetrapeptide Diketopiperazine from an Australian Mud Dauber Wasp-Associated Aspergillus sp. (CMB-W031)

Quezada, Michelle; Shang, Zhuo; Kalansuriya, P.; Salim, Angela A.; Lacey, Ernest; Capon, Robert J.

IRUOR Home
→
Scholarly Publications
→
Scholarly Publications of Academic Members
→
Faculty of Medicine
→
Department of Biochemistry
→
View Item

dc.contributor.author	Quezada, Michelle
dc.contributor.author	Shang, Zhuo
dc.contributor.author	Kalansuriya, P.
dc.contributor.author	Salim, Angela A.
dc.contributor.author	Lacey, Ernest
dc.contributor.author	Capon, Robert J.
dc.date.accessioned	2023-09-13T05:21:01Z
dc.date.available	2023-09-13T05:21:01Z
dc.date.issued	2017-02-24
dc.identifier.citation	TY - JOUR T1 - Waspergillamide A, a Nitro depsi-Tetrapeptide Diketopiperazine from an Australian Mud Dauber Wasp-Associated Aspergillus sp. (CMB-W031) AU - Quezada, Michelle AU - Shang, Zhuo AU - Kalansuriya, Pabasara AU - Salim, Angela A. AU - Lacey, Ernest AU - Capon, Robert J. Y1 - 2017/04/28 PY - 2017 DA - 2017/04/28 N1 - doi: 10.1021/acs.jnatprod.6b01062 DO - 10.1021/acs.jnatprod.6b01062 T2 - Journal of Natural Products JF - Journal of Natural Products JO - J. Nat. Prod. SP - 1192 EP - 1195 VL - 80 IS - 4 PB - American Chemical Society SN - 0163-3864 M3 - doi: 10.1021/acs.jnatprod.6b01062 UR - https://doi.org/10.1021/acs.jnatprod.6b01062 ER -	en_US
dc.identifier.uri	http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/14624
dc.description.abstract	Chemical profiling of extracts from a mud dauber wasp-associated fungus, Aspergillus sp. (CMB-W031), revealed a remarkably diverse array of secondary metabolites, with many biosynthetic gene clusters being transcriptionally responsive to specific culture conditions. Chemical fractionation of a jasmine rice cultivation yielded many known fungal metabolites, including the highly cytotoxic (−)-stephacidin B and an unprecedented nonribosomal peptide synthase derived nitro depsi-tetrapeptide diketopiperazine, waspergillamide A (1). All structures were assigned by detailed spectroscopic analysis and, where appropriate, chemical degradation and Marfey’s analysis.	en_US
dc.language.iso	en	en_US
dc.publisher	ACS Publications	en_US
dc.title	Waspergillamide A, a Nitro depsi-Tetrapeptide Diketopiperazine from an Australian Mud Dauber Wasp-Associated Aspergillus sp. (CMB-W031)	en_US
dc.type	Article	en_US