Citation:Napagoda M, Rulíšek L, Jančařík A, Klívar J, Šámal M, Stará IG, Starý I, Šolínová V, Kašička V, Svatoš A. Azahelicene Superbases as MAILD Matrices for Acidic Analytes. Chempluschem. 2013 Sep;78(9):937-942. doi: 10.1002/cplu.201300258. Epub 2013 Aug 19. PMID: 31986738.
Date:2013-08-19
Abstract:
Fitting the profile: A superbasic 1,14-diaza[5]helicene can serve as an efficient, ionless matrix for matrix-assisted ionization/laser desorption (MAILD) spectrometry. The matrix outperforms other bases by acting as a kinetically active proton sponge and is highly suitable for high-throughput metabolomics analysis. There is a correlation between the basicity (and proton-sponge character) of matrices and their efficacy in MAILD-MS.