Abstract:
In the article titled “Gmelina arborea Roxb. (Family: Verbe-
naceae) Extract Upregulates the β-Cell Regeneration in STZ
Induced Diabetic Rats” [1], the following statement should
be added as the second paragraph under the Animals subsec-
tion in the Materials and Methods:
Animals in the healthy control, diabetic control, and
glibenclamide-treated groups overlap with another article
titled “Antihyperglycaemic, Antihyperlipidaemic and β Cell
Regenerative Effects of Spondias pinnata (Linn. f.) Kurz. Bark
Extract on Streptozotocin Induced Diabetic Rats” [2], as the
two studies were conducted in parallel by the same group.
The use of common animals in control groups reduced the
number of animals used in the experiments, an important
aspect of the 3Rs principle in ethics involving animal
research [3]. Furthermore, a common methodology was
followed in the two studies [1, 2].