Abstract:
Present study was undertaken to validate anti-cancer property of Alpinia calcarata and Solanum surattense in immunosuppressed mice, rats and human cell lines. Rat xenograft model of HeLa cells (human) was established. Rats were orally fed with both plant extracts at doses of 50 mg/kg and 100 mg/kg for three weeks. On the 21st day, two hours after treatment, Cyclophosphamide was orally given at a dose of 50 mg/kg to all rats. Right armpit of immunosuppressed rats was subcutaneously inoculated with 0.2 ml HeLa single-cell suspension.
