A laboratory-based pilot study on anticancer property of Alpinia calcarata (“Araththa”) and Solanum surattense (“Ela Batu”) in immunosuppressed mice, rats and human cell lines

dc.contributor.author	Kithmini, K.K.A.
dc.contributor.author	Chandana, E.P.S.
dc.contributor.author	De Silva, P.M.C.S.
dc.contributor.author	Hettiihewa, M.
dc.date.accessioned	2022-04-06T09:06:49Z
dc.date.available	2022-04-06T09:06:49Z
dc.date.issued	2022-01-19
dc.identifier.issn	1391-8796
dc.identifier.uri	http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/5651
dc.description.abstract	Present study was undertaken to validate anti-cancer property of Alpinia calcarata and Solanum surattense in immunosuppressed mice, rats and human cell lines. Rat xenograft model of HeLa cells (human) was established. Rats were orally fed with both plant extracts at doses of 50 mg/kg and 100 mg/kg for three weeks. On the 21st day, two hours after treatment, Cyclophosphamide was orally given at a dose of 50 mg/kg to all rats. Right armpit of immunosuppressed rats was subcutaneously inoculated with 0.2 ml HeLa single-cell suspension.	en_US
dc.language.iso	en	en_US
dc.publisher	Faculty of Science, University of Ruhuna, Matara, Sri Lanka	en_US
dc.subject	A. calcarata	en_US
dc.subject	Anti-cancer	en_US
dc.subject	Cyclophosphamide	en_US
dc.subject	S. surattense	en_US
dc.subject	Xenograft	en_US
dc.title	A laboratory-based pilot study on anticancer property of Alpinia calcarata (“Araththa”) and Solanum surattense (“Ela Batu”) in immunosuppressed mice, rats and human cell lines	en_US
dc.type	Article	en_US