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Browsing Department of Pharmacology by Subject "Paraquat"

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Adherence to the current guidelines in the management of paraquat poisoning

Jayasinghe, S. S.; Fernando, A. (Galle Medical Association, 2013-11-01)

Background: Self-poisoning with paraquat (PQ) is a major health problem with 60 -70% fatality. Fuller’s earth is the mainstay of therapy as other treatment modalities are controversial. Current management guidelines of ...
Effects of Deliberate Ingestion of Organophosphate or Paraquat on Brain Stem Auditory-Evoked Potentials

Jayasinghe, S. S.; Pathirana, K. D. (Springer, 2011-08-11)

Organophosphate (OP) and paraquat (PQ) ingestion is a serious health problem. A common pathology behind OP or PQ poisoning is the generation of reactive oxygen species (ROS) which is known to cause ototoxicity. The aim of ...
Neurotoxic effects of paraquat

Jayasinghe, S. S.; Seneviratne, S. A. (Galle Medical Association, 2016-10-15)

Paraquat (1, 1’ - dimethyl - 4, 4 - dipyridyl) is a bipyridyl compound. It was first marketed in 1962 as a broad-spectrum, non-selective and contact herbicide after having been described first byWeidel and Rosso in 1882. ...
Simple and sensitive liquid chromatography–tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies

Wunnapuk, Klintean; Medley, Gregory A.; Liu, Xin; Grice, Jeffrey E.; Jayasinghe, S. S.; Gawarammana, I.; Buckley, Nicholas A.; Roberts, Michael S. (Elsevier, 2011-10-15)

Simple, sensitive and specific liquid chromatography–tandem mass spectrometry (LC–MS/MS) methods have been developed and validated for quantification of paraquat (PQ) in plasma and urine. Plasma and urine sample preparation ...

Browsing Department of Pharmacology by Subject "Paraquat"

Browsing Department of Pharmacology by Subject "Paraquat"

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