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Browsing Department of Medical Laboratory Science by Author

Browsing Department of Medical Laboratory Science by Author "Attanayake, A.P."

Now showing items 1-8 of 8

Acute and 28-Day Repeated-Dose Oral Toxicity Assessment of Abelmoschus moschatus Medik. in Healthy Wistar Rats

Amarasiri, S.S.; Attanayake, A.P.; Arawwawala, L.D.A.M.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (Hindawi, 2020-06-19)

Abelmoschus moschatus Medik. (family: Malvaceae) has a long history of being used as a folk medicine in Sri Lanka. Despite the therapeutic use of this plant in traditional medicine, leaves of A. moschatus have not been ...
Animal models of chronic kidney disease: Screening tool to investigate nephroprotective effects of natural products

Amarasiri, S.S.; Attanayake, A.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (Innovative education and scientific research foundation, 2018-06-01)

Animals are used as experimental models to reproduce human diseases. To date, various animal models have been successfully developed by numerous methods to simulate human diseases including chronic kidney disease (CKD). ...
Asparagus falcatus L. (Asparagaceae) leaf extracts attenuate doxorubicin- induced renal toxicity via antioxidant, anti- inflammatory and anti-apoptotic pathways

Amarasiri, S.S.; Attanayake, A.P.; Mudduwa, L.K.B.; Jayatilaka, K.A.P.W. (Taylor & Francis, 2022-05-30)

The search for therapeutic agents that improve kidney function against doxorubicin-induced renal tox icity is important. Herein, the potential nephroprotective activity by Asparagus falcatus L. (AF, Asparagaceae) leaf ...
Nephroprotective activity of Vetiveria zizanioides (L.) Nash supplement in doxorubicin-induced nephrotoxicity model of Wistar rats. Journal of Food Biochemistry

Amarasiri, S.S.; Attanayake, A.P.; Arawwawala, L.D.A.M.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (WILEY-BlACKWELL, 2021-08-02)

The nephroprotective effect of standardized aqueous root extract of Vetiveria ziza nioides (L.) Nash (Family: Poaceae) was investigated in doxorubicin-induced (20 mg/ kg, ip) experimental nephrotoxicity model of Wistar ...
Nephroprotective mechanisms of Ambrette (Abelmoschus moschatus Medik.) leaf extracts in adriamycin mediated acute kidney injury model of Wistar rats

Amarasiri, S.S.; Attanayake, A.P.; Mudduwa, L.K.B.; Jayatilaka, K.A.P.W. (Elsevier B.V., 2022-03-23)

Ethnopharmacological relevance: Ambrette (Abelmoschus moschatus Medik., Family: Malvaceae) is a common Ay urvedic herbal medicine used in the treatment of kidney-related diseases, in the forms of tea, medicated oil, ...
Optimization of 25% Sulfosalicylic Acid Protein-to-Creatinine Ratio for Screening of Low-Grade Proteinuria

Jinadasa, A.G.R.G.; Srimantha, L.A.S.M.; Siriwardana, I.D.; Gunawardana, K.B.; Attanayake, A.P. (Hindawi, 2021-01-28)

Proteinuria is an important prognostic marker in the diagnosis and management of kidney diseases. Sulfosalicylic acid method (SSA) is a simple, low cost, qualitative test, widely used to assess proteinuria. ,e aim of this ...
South Asian medicinal plants and chronic kidney disease: a review

Amarasiri, S.S.; Attanayake, A.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (TMR, 2020-08-01)

Chronic kidney disease remains as one of the serious health issues in South Asia. The paucity of effective pharmacotherapy targeting the management of chronic kidney disease has led to a search for alternative pharmacologic ...
Standardized aqueous stem bark extract of Gmelina arborea Roxb. possesses nephroprotection against adriamycin-induced nephrotoxicity in Wistar rats

Amarasiri, S.S.; Attanayake, A.P.; Arawwawala, L.D.A.M.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (Taylor & Francis, 2020-08-30)

Nephrotoxicity is a major limitation of adriamycin (ADR) chemotherapy. We hypothesized that adminis tration of standardized aqueous bark extract of Gmelina arborea Roxb. (GA) (Family; Verbenaceae), a traditional therapeutic ...

Browsing Department of Medical Laboratory Science by Author "Attanayake, A.P."

Browsing Department of Medical Laboratory Science by Author "Attanayake, A.P."

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