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Browsing Department of Medical Laboratory Science by Title

Browsing Department of Medical Laboratory Science by Title

Now showing items 1-20 of 106

Acute and 28-Day Repeated-Dose Oral Toxicity Assessment of Abelmoschus moschatus Medik. in Healthy Wistar Rats

Amarasiri, S.S.; Attanayake, A.P.; Arawwawala, L.D.A.M.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (Hindawi, 2020-06-19)

Abelmoschus moschatus Medik. (family: Malvaceae) has a long history of being used as a folk medicine in Sri Lanka. Despite the therapeutic use of this plant in traditional medicine, leaves of A. moschatus have not been ...
Analysis of mortality pattern of chronic kidney disease of uncertain etiology (CKD-u) at a single center, girandurukotte: Sri Lanka

Hettiarachchi, T.W.; Nanayakkara, N.; Wijetunge, S.; Gunaratne, L.; Abeysekara, D.T.J.; Badurdeen, Z.; Fernando, W.B.N.T.; Hanarasinghe, R.; Hemage, K.R.D.; Somarathna, Y.R.; Sudeshika, S.H.T.; Dharmaratne, S.D. (2016)

Introduction and objectives: CKD-u was first reported in the North Central Province of Sri Lanka in the early 1990s; over the last 15 years its prevalence has gradually increased and presently, it isamajor health problem ...
An Analysis of Rate of Progression and Associated Risk Factors of Chronic Kidney Disease of Uncertain Etiology in Sri Lanka

Hettiarachchi, T.W.; Sudeshika, T.; Fernando, B.N.T.W.; Abeysundara, H.T.K.; Hemage, R.D.; Badurdeen, Z.; Hanarasinghe, R.; Wijetunge, S.; Nanayakkara, N. (Medknow Publications, 2021)

Chronic kidney disease of uncertain etiology (CKD-u) is an important public health issue in Sri Lanka and around the world, but published evidence of the progression of this disease is scanty. Our aim is to analyze the ...
Anemia in Sri Lanka: A Literature Review

Amarasingha, A. A. Dinusha S.; Silva, H. J. Ruwindi L.; Perera, P. Shiromi; Premawardhena, Anuja P. (Taylor & Francis, 2022-04-28)

Anemia is a global health problem. This paper reviews literature on the prevalence of anemia in Sri Lanka. We searched EBSCO (Elton Bryson Stephens Company), Cochrane Library, and Medline for articles on prevalence and ...
Animal models of chronic kidney disease: Screening tool to investigate nephroprotective effects of natural products

Amarasiri, S.S.; Attanayake, A.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (Innovative education and scientific research foundation, 2018-06-01)

Animals are used as experimental models to reproduce human diseases. To date, various animal models have been successfully developed by numerous methods to simulate human diseases including chronic kidney disease (CKD). ...
Anthracycline-Induced Cardiotoxicity in Breast Cancer Patients from Southern Sri Lanka: An Echocardiographic Analysis

Sandamali, J.A.N.; Hewawasam, R.P.; Fernando, M.A.C.S.S.; Jayatilaka, K.A.P.W.; Madurawe, R.D.; Sathananthan, P.P.; Ekanayake, U.; Horadugoda, J. (Hindawi, 2020-11-16)

Anthracycline-induced cardiotoxicity has never been investigated in Sri Lanka. Therefore, this study was conducted to determine the prevalence of anthracycline-induced cardiotoxicity in breast cancer patients using ...
Antibiotic use in poultry production; a cross-sectional study in a selected district in Sri Lanka

Ubeysekara, H.A.; Ranaweera, N.P.N.M.; Peiris, H.H.; Wijayaratne, W.M.D.G.B. (Galle Medical Association, 2021-08-14)

Introduction: Rampant use of antibiotics in animal husbandry contributes significantly to the development and spread of antibiotic resistance. This study determines the antibiotic activity in poultry feed and assesses the ...
Antimicrobial and antioxidant activities of Plectranthus zeylanicus Benth

Napagoda, M. T.; De Soyza, W. S. G.; Wijesiriwardhana, P.; Qader, M. M.; Wijayaratne, W. M. D. G. B.; Nagahawatte, A. de Silva; Jayasinghe, L. (University of Peradeniya, 2016-11)

Plectranthus zeylanicus Benth. (Iruveriya) is a perennial herb extensively used in traditional medicine in Sri Lanka for treating fever, asthma, dysentery, diarrhoea, chronic liver diseases etc. Despite the wide array ...
Are Incident Reporting Systems in Healthcare Systems a Requirement for Improving Patient Safety? A Review

Fernando, G.H.S.; Bandara, Thushari; Purva, Makani (International Journal of Health System Resilience, 2023-02-05)

Adverse events such as medical errors, injuries, or equipment failures which could harm patients, caregivers, or other individuals or has the potential to harm them are known as medical incidents. Avoidance of unintended ...
Asparagus falcatus L. (Asparagaceae) leaf extracts attenuate doxorubicin- induced renal toxicity via antioxidant, anti- inflammatory and anti-apoptotic pathways

Amarasiri, S.S.; Attanayake, A.P.; Mudduwa, L.K.B.; Jayatilaka, K.A.P.W. (Taylor & Francis, 2022-05-30)

The search for therapeutic agents that improve kidney function against doxorubicin-induced renal tox icity is important. Herein, the potential nephroprotective activity by Asparagus falcatus L. (AF, Asparagaceae) leaf ...
Assessment of Knowledge and Healthcare Related Practices of Caregivers Regarding Home Management of Children with Nephrotic Syndrome

Madhushani, J.S.S.; Bandara, W.V.R.T.D.G. (University of Sri Jayewardenepura, 2021)

Introduction: Nephrotic Syndrome (NS) is the commonest chronic glomerular disorder characterized by heavy proteinuria, hypoproteinaemia, oedema and hyperlipidaemia. Parental motivation and involvement are essential for ...
An assessment of the sleeping pattern in healthy infants

Madhushika, N. G. H. (Sri Lanka College of Paediatricians, 2021-09-05)

Background: Sleep plays a significant role in good physiological state and well-being throughout life. Sleep is necessary for children because it directly impacts mental and physical development. Objective: To ...
Awareness of female malignancies among women and their partners in Southern Sri Lanka and implications for screening: a cross sectional study

Witharana, Chamindri; Wijesiriwardhana, Prabhavi; Jayasekara, Kalani; Kumari, Priyanka; Rodrigo, Chaturaka (BMC, 2015-11-25)

Background: The incidences of breast, cervical and uterine malignancies continue to increase in Sri Lanka. It is important to explore the awareness of both women and their male partners regarding these malignancies ...
Bioactivity of cinnamon with special emphasis on diabetes mellitus: A review

Bandara, Thushari; Uluwaduge, Inoka; Jansz, E.R. (Informa UK, Ltd., 2011-10-19)

Cinnamon is the oldest spice and has been used by several cultural practices for centuries. In addition to its culinary uses, cinnamon possesses a rising popularity due to many stated health benefits. Out of the large ...
Body composition among Sri Lankan infants by 18O dilution method and the validity of anthropometric equations to predict body fat against 18O dilution

Bandara, T.; Hettiarachchi, M.; Liyanage, C.; Amarasena, S.; Wong, William Wai-Lun (BMC Pediatrics, 2015-05-06)

Background Body composition indicators provide a better guidance for growth and nutritional status of the infants. This study was designed to (1) measure the body composition of the Sri Lankan infants using a reference ...
Bovine tuberculosis: a histopathological study of the lung lesions

Amarasiri, P.G.I.D.; Ramanayake, R.M.T.M.; Karawita, A.C.; Perera, K.U.E.; Jayaweera, W.R.; Gunawardena, G.S.P.De.S (University of Peradeniya, 2015-11)

Bovine tuberculosis caused by Mycobacterium species is a chronic and contagious disease that results in loss of production leading to high economic losses in cattle industry. Moreover, some of the cattle Mycobacterium ...
Cardioprotective potential of Murraya koenigii (L.) Spreng. leaf extract against doxorubicin-induced cardiotoxicity in rats

Sandamali, J.A.N.; Hewawasam, R.P.; Jayatilaka, K.A.P.W.; Mudduwa, L.K.B. (Hindawi, 2020-03-16)

Dose-dependent cardiotoxicity of doxorubicin may lead to irreversible congestive heart failure. Although multiple mechanisms are involved, generation of free radicals is the most commonly postulated mechanism. +erefore, ...
CECOCOLIC INTUSSUSCEPTION IN AN ASIAN ELEPHANT (ELEPHAS MAXIMUS) IN SRI LANKA ASSOCIATED WITH CHRONIC HEPATO INTESTINAL SCHISTOSOMIASIS: FIRST CASE REPORT

Karawita, A.C.; Rajapakse, R.C.; Amarasiri, P.G.I.D.; Ramanayake, R.M.T.M.; Jayaweera, W.R.; Bollinger, T.K.; Gunawardena, G.S.P.De.S (INASP, 2015-12-30)

A 25 year old female captive Asian elephant weighing approximately 3000kgs died and was subjected to a complete necropsy within 5 hours post mortem. Grossly, the elephant had sub-cutaneous edema, cecocolic intussusception ...
Changes in the demographic pattern of animal rabies in the Central province of Sri Lanka

Ramanayake, R.M.T.M.; Amarasiri, P.G.I.D.; Karawita, A.C.; Jayaweera, W.R.; Obayashi, Y.; Hiko, T.; Gunawardena, G.S.P.de.S. (2015)

Rabies is a fatal zoonotic viral disease of public health importance endemic in Sri Lanka. Poor surveillance, underreporting in many developing countries and frequent misdiagnosis of rabies have lead to underestimation ...
characteristic features of patients with CKD and CKDu in Girandurukotte and Wilgamuwa, SriLanka

Fernando, W.B.N.T.; Sudeshika, S.H.T.; Hettiarachchi, T.W.; Ranasinghe, J.G.S.; Nanayakkara, N. (University of Peradeniya, 2018)

Chronic Kidney Disease of uncertain aetiology (CKDu) is an endemic disease among agricultural workers in SriLanka. This study was designed to find the unique characteristics of CKDu in Girandurukotte and Wilgamuwa. A ...

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