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Browsing Department of Medical Laboratory Science by Author

Browsing Department of Medical Laboratory Science by Author "Peiris, H.H."

Now showing items 1-13 of 13

Antibiotic use in poultry production; a cross-sectional study in a selected district in Sri Lanka

Ubeysekara, H.A.; Ranaweera, N.P.N.M.; Peiris, H.H.; Wijayaratne, W.M.D.G.B. (Galle Medical Association, 2021-08-14)

Introduction: Rampant use of antibiotics in animal husbandry contributes significantly to the development and spread of antibiotic resistance. This study determines the antibiotic activity in poultry feed and assesses the ...
Do Breast Cancer Risk Factors Affect the Survival of Breast Cancer Patients in Southern Sri Lanka?

Peiris, H.H.; Mudduwa, L.K.B.; Thalagala, N.I.; Jayatilaka, K.A.P.W. (Asian Pac J Cancer Prev,, 2017)

Background: Breast cancer continues to be a major cause of morbidity among women in Sri Lanka. Possible effects of etiological risk factors on breast cancer specific survival (BCSS) of the disease is not clear.This study ...
Effect of morphological preservation artifacts on the quality of immuno histochemical staining forER and Her-2

Peiris, H.H.; Mudduwa, L.K.B.; Liyanage, T.; Ranasinghe, J.G.S. (Galle Medical Journal, 2013)

Introduction: The most commonly encountered morphological preservation artifacts in the histological assessment of breast cancer include retraction of tumour cell clusters from the stroma, cytoplasmic retraction and ...
Elevated pre-surgical CA15-3: does it predict the short-term disease-free survival of breast cancer patients without distant metastasis?

Mudduwa, L.K.B.; Wijayaratne, G.B.; Peiris, H.H.; Gunasekera, S.N.; Abeysiriwardhana, D.; Liyanage, N. (International Journal of Women's Health, 2018)

Background: CA15-3 is the most commonly used tumor marker in breast cancer. Its prognostic role has been described in the metastatic setting, but the role of pre-surgical CA15-3 in the assessment of patients with breast ...
Evaluation of a staining technique using toluidine blue in comparison to Gram stain for direct detection of bacteria in the positive blood culture broth

Kumara, Y.N.B.; Wickramasinghe, S.S.; Peiris, H.H. (Galle Medical Association, 2021-09)

Background Direct Gram stain (GS) smear of positive blood culture broth remains the cornerstone of rapid identification of the causative microorganism and determining the empirical antibiotic treatment in septicaemia. ...
Immunohistochemical assessment of PTEN expression and itsassociation with tamoxifen resistance in ER positive breast cancers

Wijesiri, T.W.; Peiris, H.H.; Mudduwa, L.K.B. (Galle Medical Association, 2021-09-15)

Introduction: Although Estrogen Receptor (ER) positivity is a good prognostic factor in breast carcinoma (BC), a subset of patients experiences poor disease-free survival (DFS). Mutation in phosphatase and tensin homologue ...
Immunohistochemical detection of Claudin low breast cancer; which subcellular level to be assessed?

Mudduwa, L.K.B.; Peiris, H.H.; Gunasekera, S.N.; Liyanage, T.G.; Abeysiriwardhana, D.S. (University of Sri Jayewardenepura, 2017-08-18)

Objectives: Claudin low breast cancers are often high grade, triple negative tumours with poor prognosis. They are identified at genetic level and are not diagnosed routinely by immunohistochemistry. The objective was ...
Knowledge, attitudes, and practices towards COVID-19 among Sri Lankan undergraduates studying in countries affected by COVID -19: A comparative study

Amarasingha, A.A.D.S.; Peiris, H.H.; Amarasingha, A.A.B.N. (University of Sri Jayewardenepura, 2021-10-15)

Background: University students are usually self-determined and willing to live independently; however, they have lack of life experience. Since they are living in a limited space and close proximity, they are ...
Nottingham grade; does it influence the survival of operable breast cancer patients across all TNM stages?

Peiris, H.H.; Mudduwa, L.K.B.; Thalagala, N.; Jayatilaka, K.; Ekanayaka, U.; Horadugoda, J. (Elsevier, 2015-12-01)

Aim/Background: Lymph node stage (LNS), tumour size and Nottingham grade (NG) are considered the most im portant prognostic factors of breast cancer (BC).However, NG is not yet incorporated in the long used TNM staging system ...
Outcome based validation of Nottingham Prognostic Index in a Sri Lankan setting

Peiris, H.H.; Mudduwa, L.K.B.; Thalagala, N.I.; Jayatilaka, K.A.P.W.; Ekanayaka, U.; Horadugoda, J. (University of Ruhuna, Matara, Sri Lanka, 2016-03-19)

Nottingham prognostic index (NPI) is widely used to stratify breast cancer (BC) patients into prognostic groups; good (I=≤3.4), moderate (II=3.4-5.4) and poor (III=>5.4). Although it has been in use for many years it has ...
Predictive Factors of Breast Cancer Specific Survival of Patients Who Received Neoadjuvant Chemotherapy

Peiris, H.H.; Mudduwa, L.K.B.; Thalagala, N.I.; Jayatilake, K.A.P.W.; Ekanayaka, U.; Horadugoda, J. (General Sir John Kotelawala Defence University, 2015-08)

Neoadjuvant Chemotherapy (NAC) is a safe and effective therapeutic approach for larger primary and locally advanced breast cancer. The objective of this study was to determine the factors predicting the survival of ...
Predictors of Breast Cancer Specific Survival of Patients with Node-negative Breast Cancer

Peiris, H.H.; Mudduwa, L.K.B.; Thalagala, N.I.; Jayathilaka, K.A.P.W.; Ekanayaka, U.; Horadugoda, J. (University of Ruhuna, Matara, Sri Lanka, 2016-03-19)

The axillary lymph node status is one of the most important prognostic factors of breast cancer (BC). Increasing the number of positive lymph nodes decreases the survival. It is important to know what factors predict the ...
Risk factors and clinico-pathological profile of Triple Negative Breast Cancer; A comparative study done in southern province of Sri Lanka

Peiris, H.H.; Mudduwa, L.K.B.; Thalagala, N.I.; Jayatilaka, K.A.P.W. (University of Sri Jayewardenepura, 2015-06-11)

Objectives: To compare the risk factors and clinico-pathological features of Triple Negative Breast Cancer (TNBC) and non-TNBC in females in Southern Province of Sri Lanka Methods: This retrospective study included ...

Browsing Department of Medical Laboratory Science by Author "Peiris, H.H."

Browsing Department of Medical Laboratory Science by Author "Peiris, H.H."

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