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Browsing Department of Medical Laboratory Science by Author

Browsing Department of Medical Laboratory Science by Author "Ramanayake, R.M.T.M."

Now showing items 1-10 of 10

Bovine tuberculosis: a histopathological study of the lung lesions

Amarasiri, P.G.I.D.; Ramanayake, R.M.T.M.; Karawita, A.C.; Perera, K.U.E.; Jayaweera, W.R.; Gunawardena, G.S.P.De.S (University of Peradeniya, 2015-11)

Bovine tuberculosis caused by Mycobacterium species is a chronic and contagious disease that results in loss of production leading to high economic losses in cattle industry. Moreover, some of the cattle Mycobacterium ...
CECOCOLIC INTUSSUSCEPTION IN AN ASIAN ELEPHANT (ELEPHAS MAXIMUS) IN SRI LANKA ASSOCIATED WITH CHRONIC HEPATO INTESTINAL SCHISTOSOMIASIS: FIRST CASE REPORT

Karawita, A.C.; Rajapakse, R.C.; Amarasiri, P.G.I.D.; Ramanayake, R.M.T.M.; Jayaweera, W.R.; Bollinger, T.K.; Gunawardena, G.S.P.De.S (INASP, 2015-12-30)

A 25 year old female captive Asian elephant weighing approximately 3000kgs died and was subjected to a complete necropsy within 5 hours post mortem. Grossly, the elephant had sub-cutaneous edema, cecocolic intussusception ...
Changes in the demographic pattern of animal rabies in the Central province of Sri Lanka

Ramanayake, R.M.T.M.; Amarasiri, P.G.I.D.; Karawita, A.C.; Jayaweera, W.R.; Obayashi, Y.; Hiko, T.; Gunawardena, G.S.P.de.S. (2015)

Rabies is a fatal zoonotic viral disease of public health importance endemic in Sri Lanka. Poor surveillance, underreporting in many developing countries and frequent misdiagnosis of rabies have lead to underestimation ...
Effect of lipid peroxidation on protein quality of snakehead fish (channa striata) stored at -10°C for 28 days

Ramanayake, R.M.T.M.; Hiniduma, H.L.S.K.; Withanage, T.J.; Munasinghe, D.M.S. (University of Peradeniya, 2015-11)

The experiment was conducted to determine the progression of lipid peroxidation and the effects of it on protein quality of Snakehead fish (Channa striata) stored at -10 oC for 28 days. Fish were harvested from Victoria ...
The Effects of Lipid Peroxidation and Storage Conditions on Keeping Quality of Snake Head Fish (Channastriata)

Ramanayake, R.M.T.M.; Sakai, T.; Munasinghe, D.M.S. (University of Peradeniya, 2014-12-15)

The experiment was conducted to determine the progression of lipid peroxidation and the effects of it on Snake head fish (Channastriata) stored at -100C for 28 days. Fish were harvested from Victoria reservoir and ...
Generation of Helix-Loop-Helix (HLH) peptide inhibitor of the interaction between human CTLA-4 and B7

Ramanayake, R.M.T.M.; Fujiwara, D.; Michigami, M.; Sugiura, K.; Fujii, I. (2018)
Generation of molecular-targeting helix-loop-helix peptides for inhibition of the interaction between cytotoxic T-lymphocyte-associated protein 4 and B7 in the dog

Ramanayake, R.M.T.M.; Fujiwara, Daisuke; Michigami, Masataka; Watanabe, Shunichi; Ye, Zhengmao; Ueda, Atsuko; Kanegi, Ryoji; Hatoya, Shingo; Fujii, Ikuo; Sugiura, Kikuya (J-STAR, 2022-06-24)

Blocking the interaction between CD28 and B7 by cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a potent immune checkpoint that prevents damage to host tissues from excessive immune responses. However, it also ...
An Immune-Stimulatory Helix–Loop–Helix Peptide: Selective Inhibition of CTLA-4–B7 Interaction

Ramanayake, R.M.T.M.; Michigami, Masataka; Ye, Zhengmao; Uyeda, Atsuko; Inoue, Norimitsu; Sugiura, Kikuya; Fujii, Ikuo; Fujiwara, Daisuke (ACS publcations, 2019-12-16)

Molecular-targeting peptides and mini-proteins are promising alternatives to antibodies in a wide range of applications in bioscience and medicine. We have developed a helix−loop−helix (HLH) peptide as an alternative ...
New Class of Drug Modalities: Directed Evolution of a De Novo Designed Helix–Loop–Helix Peptide to Bind VEGF for Tumor Growth Inhibition

Michigami, Masataka; Ramanayake, R.M.T.M.; Suzuki, Miho; Ishizako, Hirotsugu; Notsu, Kunpei; Sugiura, Kikuya; Fujii, Ikuo (ACS publcations, 2022-02-17)

As a small affinity molecule to serve as an alternative to antibodies, we have developed a conformationally constrained peptide with a de novo designed helix−loop−helix (HLH) scaffold. To evaluate its potential for ...
Sensitivity and specificity of the Negri body test using Sellers’ stain in the diagnosis of rabies in dogs

Ramanayake, R.M.T.M.; Amarasiri, P.G.I.D.; Karawita, A.C.; Jayaweera, W.R.; Obayashi, Y.; Hiko, T.; Gunawardena, G.S.P.De.S (2015)

Rabies is an invariably fatal zoonotic viral disease which infects all mammalian species. Dog rabies is the main source of infection for human disease. Confirmation of rabies infection requires laboratory testing of ...

Browsing Department of Medical Laboratory Science by Author "Ramanayake, R.M.T.M."

Browsing Department of Medical Laboratory Science by Author "Ramanayake, R.M.T.M."

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