dc.contributor.author |
Shang, Zhuo |
|
dc.contributor.author |
Khalil, Zeinab |
|
dc.contributor.author |
Li, Li |
|
dc.contributor.author |
Salim, Angela A. |
|
dc.contributor.author |
Quezada, Michelle |
|
dc.contributor.author |
Kalansuriya, P. |
|
dc.contributor.author |
Capon, Robert J. |
|
dc.date.accessioned |
2023-09-13T05:13:07Z |
|
dc.date.available |
2023-09-13T05:13:07Z |
|
dc.date.issued |
2016-08-18 |
|
dc.identifier.citation |
TY - JOUR T1 - Roseopurpurins: Chemical Diversity Enhanced by Convergent Biosynthesis and Forward and Reverse Michael Additions AU - Shang, Zhuo AU - Khalil, Zeinab AU - Li, Li AU - Salim, Angela A. AU - Quezada, Michelle AU - Kalansuriya, Pabasara AU - Capon, Robert J. Y1 - 2016/09/02 PY - 2016 DA - 2016/09/02 N1 - doi: 10.1021/acs.orglett.6b02099 DO - 10.1021/acs.orglett.6b02099 T2 - Organic Letters JF - Organic Letters JO - Org. Lett. SP - 4340 EP - 4343 VL - 18 IS - 17 PB - American Chemical Society SN - 1523-7060 M3 - doi: 10.1021/acs.orglett.6b02099 UR - https://doi.org/10.1021/acs.orglett.6b02099 ER - |
en_US |
dc.identifier.uri |
http://ir.lib.ruh.ac.lk/xmlui/handle/iruor/14621 |
|
dc.description.abstract |
Cultures of the estuarine fungus Penicillium roseopurpureum (CMB-MF038) yielded a diverse array of polyketides, many of which were related via a highly convergent biosynthetic pathway. In addition to revising and assigning structures, and documenting chemical and biological properties, pro-drug cytotoxic properties were attributed to roseopurpurins H (10) and I (11) on the basis of in situ reverse Michael addition to a cytotoxic Michael acceptor (12). |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
ACS Publications |
en_US |
dc.title |
Roseopurpurins: Chemical Diversity Enhanced by Convergent Biosynthesis and Forward and Reverse Michael Additions |
en_US |
dc.type |
Article |
en_US |